Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Alcoholic hepatitis is characterized by intense liver inflammation driven by excessive cytokines and chemokines production and immune cell infiltration. Here the authors identify a super-enhancer that regulates the expression of multiple CXCL chemokines in alcoholic hepatitis and may be a potential...

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Autores principales:	Mengfei Liu, Sheng Cao, Li He, Jinhang Gao, Juan P. Arab, Huarui Cui, Weixia Xuan, Yandong Gao, Tejasav S. Sehrawat, Feda H. Hamdan, Meritxell Ventura-Cots, Josepmaria Argemi, William C. K. Pomerantz, Steven A. Johnsen, Jeong-Heon Lee, Fei Gao, Tamas Ordog, Philippe Mathurin, Alexander Revzin, Ramon Bataller, Huihuang Yan, Vijay H. Shah
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/00c1cb666647413b9cdcbd808e6d8ec6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:00c1cb666647413b9cdcbd808e6d8ec62021-12-02T16:24:57ZSuper enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis10.1038/s41467-021-24843-w2041-1723https://doaj.org/article/00c1cb666647413b9cdcbd808e6d8ec62021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24843-whttps://doaj.org/toc/2041-1723Alcoholic hepatitis is characterized by intense liver inflammation driven by excessive cytokines and chemokines production and immune cell infiltration. Here the authors identify a super-enhancer that regulates the expression of multiple CXCL chemokines in alcoholic hepatitis and may be a potential therapeutic target.Mengfei LiuSheng CaoLi HeJinhang GaoJuan P. ArabHuarui CuiWeixia XuanYandong GaoTejasav S. SehrawatFeda H. HamdanMeritxell Ventura-CotsJosepmaria ArgemiWilliam C. K. PomerantzSteven A. JohnsenJeong-Heon LeeFei GaoTamas OrdogPhilippe MathurinAlexander RevzinRamon BatallerHuihuang YanVijay H. ShahNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mengfei Liu Sheng Cao Li He Jinhang Gao Juan P. Arab Huarui Cui Weixia Xuan Yandong Gao Tejasav S. Sehrawat Feda H. Hamdan Meritxell Ventura-Cots Josepmaria Argemi William C. K. Pomerantz Steven A. Johnsen Jeong-Heon Lee Fei Gao Tamas Ordog Philippe Mathurin Alexander Revzin Ramon Bataller Huihuang Yan Vijay H. Shah Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
description	Alcoholic hepatitis is characterized by intense liver inflammation driven by excessive cytokines and chemokines production and immune cell infiltration. Here the authors identify a super-enhancer that regulates the expression of multiple CXCL chemokines in alcoholic hepatitis and may be a potential therapeutic target.
format	article
author	Mengfei Liu Sheng Cao Li He Jinhang Gao Juan P. Arab Huarui Cui Weixia Xuan Yandong Gao Tejasav S. Sehrawat Feda H. Hamdan Meritxell Ventura-Cots Josepmaria Argemi William C. K. Pomerantz Steven A. Johnsen Jeong-Heon Lee Fei Gao Tamas Ordog Philippe Mathurin Alexander Revzin Ramon Bataller Huihuang Yan Vijay H. Shah
author_facet	Mengfei Liu Sheng Cao Li He Jinhang Gao Juan P. Arab Huarui Cui Weixia Xuan Yandong Gao Tejasav S. Sehrawat Feda H. Hamdan Meritxell Ventura-Cots Josepmaria Argemi William C. K. Pomerantz Steven A. Johnsen Jeong-Heon Lee Fei Gao Tamas Ordog Philippe Mathurin Alexander Revzin Ramon Bataller Huihuang Yan Vijay H. Shah
author_sort	Mengfei Liu
title	Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
title_short	Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
title_full	Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
title_fullStr	Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
title_full_unstemmed	Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
title_sort	super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/00c1cb666647413b9cdcbd808e6d8ec6
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Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

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