Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial

Tanapat Ratanapakorn, Watcharaporn Thongmee, Kidakarn Meethongkam, Suthasinee Sinawat, Thuss Sanguansak, Chavakij Bhoomibunchoo, Wipada Laovirojjanakul, Yosanan Yospaiboon KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Yosan...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ratanapakorn T, Thongmee W, Meethongkam K, Sinawat S, Sanguansak T, Bhoomibunchoo C, Laovirojjanakul W, Yospaiboon Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	silicone oil viscosity emulsification Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/00c8c175e8f04c9f817815482c537b59
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:00c8c175e8f04c9f817815482c537b59
record_format	dspace
spelling	oai:doaj.org-article:00c8c175e8f04c9f817815482c537b592021-12-02T08:37:52ZEmulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial1177-5483https://doaj.org/article/00c8c175e8f04c9f817815482c537b592020-02-01T00:00:00Zhttps://www.dovepress.com/emulsification-of-different-viscosity-silicone-oil-in-complicated-reti-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Tanapat Ratanapakorn, Watcharaporn Thongmee, Kidakarn Meethongkam, Suthasinee Sinawat, Thuss Sanguansak, Chavakij Bhoomibunchoo, Wipada Laovirojjanakul, Yosanan Yospaiboon KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Yosanan YospaiboonKKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, 123 Mitraparb Highway, Khon Kaen 40002, ThailandTel +66 43 348383Email yyosanan@gmail.comObjective: To study silicone oil (SO) emulsification, anatomic and visual outcome after complicated retinal detachment surgery by pars plana vitrectomy (PPV) with intraocular SO tamponade, comparing between low and high viscosity SO.Design: Randomized, double-blinded, controlled trial.Patients and Methods: Patients with complicated retinal detachment who had been surgically treated by PPV and intraocular SO tamponade were randomly divided into low viscosity (Group 1) or high viscosity (Group 2). Main Outcome Measures were rate of silicone oil emulsification, anatomic retinal reattachment and visual outcome, assessed at 1,3,6,9 and 12 months.Results: One hundred patients were divided into 50 patients in each group. The rate of silicone oil emulsification in Group 1 (63.64%) was higher than Group 2 (40%), but the difference was not statistically significant (p = 0.08). Rates of anatomic retinal reattachment were 88% in Group 1 and 90% in Group 2 (p = 0.76). For functional visual outcome, final best-corrected visual acuity (BCVA) at Month 12 compared with the baseline BCVA was improved vision 52% in Group 1 and 58% in Group 2 (p = 0.82).Conclusion: SO emulsification rate in low viscosity group is non-significantly higher than high viscosity group, but results in a comparable reattachment rate and final visual recovery. Emulsification in both groups is detected at as early as 1 month and mostly within 3 months. We recommend using either low or high viscosity SO in complicated retinal detachment surgery and removing it as early as possible to prevent the consequent serious complications.Clinical Trial Registration: ClinicalTrials.gov Identifier: NCT02988583.Keywords: silicone oil, viscosity, emulsificationRatanapakorn TThongmee WMeethongkam KSinawat SSanguansak TBhoomibunchoo CLaovirojjanakul WYospaiboon YDove Medical Pressarticlesilicone oilviscosityemulsificationOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 359-367 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	silicone oil viscosity emulsification Ophthalmology RE1-994
spellingShingle	silicone oil viscosity emulsification Ophthalmology RE1-994 Ratanapakorn T Thongmee W Meethongkam K Sinawat S Sanguansak T Bhoomibunchoo C Laovirojjanakul W Yospaiboon Y Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial
description	Tanapat Ratanapakorn, Watcharaporn Thongmee, Kidakarn Meethongkam, Suthasinee Sinawat, Thuss Sanguansak, Chavakij Bhoomibunchoo, Wipada Laovirojjanakul, Yosanan Yospaiboon KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Yosanan YospaiboonKKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, 123 Mitraparb Highway, Khon Kaen 40002, ThailandTel +66 43 348383Email yyosanan@gmail.comObjective: To study silicone oil (SO) emulsification, anatomic and visual outcome after complicated retinal detachment surgery by pars plana vitrectomy (PPV) with intraocular SO tamponade, comparing between low and high viscosity SO.Design: Randomized, double-blinded, controlled trial.Patients and Methods: Patients with complicated retinal detachment who had been surgically treated by PPV and intraocular SO tamponade were randomly divided into low viscosity (Group 1) or high viscosity (Group 2). Main Outcome Measures were rate of silicone oil emulsification, anatomic retinal reattachment and visual outcome, assessed at 1,3,6,9 and 12 months.Results: One hundred patients were divided into 50 patients in each group. The rate of silicone oil emulsification in Group 1 (63.64%) was higher than Group 2 (40%), but the difference was not statistically significant (p = 0.08). Rates of anatomic retinal reattachment were 88% in Group 1 and 90% in Group 2 (p = 0.76). For functional visual outcome, final best-corrected visual acuity (BCVA) at Month 12 compared with the baseline BCVA was improved vision 52% in Group 1 and 58% in Group 2 (p = 0.82).Conclusion: SO emulsification rate in low viscosity group is non-significantly higher than high viscosity group, but results in a comparable reattachment rate and final visual recovery. Emulsification in both groups is detected at as early as 1 month and mostly within 3 months. We recommend using either low or high viscosity SO in complicated retinal detachment surgery and removing it as early as possible to prevent the consequent serious complications.Clinical Trial Registration: ClinicalTrials.gov Identifier: NCT02988583.Keywords: silicone oil, viscosity, emulsification
format	article
author	Ratanapakorn T Thongmee W Meethongkam K Sinawat S Sanguansak T Bhoomibunchoo C Laovirojjanakul W Yospaiboon Y
author_facet	Ratanapakorn T Thongmee W Meethongkam K Sinawat S Sanguansak T Bhoomibunchoo C Laovirojjanakul W Yospaiboon Y
author_sort	Ratanapakorn T
title	Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial
title_short	Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial
title_full	Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial
title_fullStr	Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial
title_full_unstemmed	Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial
title_sort	emulsification of different viscosity silicone oil in complicated retinal detachment surgery: a randomized double-blinded clinical trial
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/00c8c175e8f04c9f817815482c537b59
work_keys_str_mv	AT ratanapakornt emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT thongmeew emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT meethongkamk emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT sinawats emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT sanguansakt emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT bhoomibunchooc emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT laovirojjanakulw emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial AT yospaiboony emulsificationofdifferentviscositysiliconeoilincomplicatedretinaldetachmentsurgeryarandomizeddoubleblindedclinicaltrial
_version_	1718398402745597952

Emulsification of Different Viscosity Silicone Oil in Complicated Retinal Detachment Surgery: A Randomized Double-Blinded Clinical Trial

Ejemplares similares