A new phenotypic classification system for dyslipidemias based on the standard lipid panel
Highlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophoresis/beta-quantification in a large number of subje...
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2021
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oai:doaj.org-article:00d7e07ea77947e29c74d7d4034f28c22021-11-28T12:38:58ZA new phenotypic classification system for dyslipidemias based on the standard lipid panel10.1186/s12944-021-01585-81476-511Xhttps://doaj.org/article/00d7e07ea77947e29c74d7d4034f28c22021-11-01T00:00:00Zhttps://doi.org/10.1186/s12944-021-01585-8https://doaj.org/toc/1476-511XHighlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophoresis/beta-quantification in a large number of subjects. The new lipoprotein phenotyping system identifies high-risk cardiovascular patients and helps direct clinical management. A major advance is that the new lipoprotein phenotypes are based on just the standard lipid panel, and thus can be automatically calculated by the clinical laboratory and widely implemented.Maureen SampsonRami A. BalloutDaniel SofferAnna WolskaSierra WilsonJeff MeeusenLeslie J. DonatoErica FaticaJames D. OtvosEliot A. BrintonRobert S. RosensonPeter WilsonMarcelo AmarRobert ShamburekSotirios K. KarathanasisAlan T. RemaleyBMCarticleCholesterolLDLLipidsLipoproteinsGeneticsCardiovascular diseaseNutritional diseases. Deficiency diseasesRC620-627ENLipids in Health and Disease, Vol 20, Iss 1, Pp 1-21 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Cholesterol LDL Lipids Lipoproteins Genetics Cardiovascular disease Nutritional diseases. Deficiency diseases RC620-627 |
| spellingShingle |
Cholesterol LDL Lipids Lipoproteins Genetics Cardiovascular disease Nutritional diseases. Deficiency diseases RC620-627 Maureen Sampson Rami A. Ballout Daniel Soffer Anna Wolska Sierra Wilson Jeff Meeusen Leslie J. Donato Erica Fatica James D. Otvos Eliot A. Brinton Robert S. Rosenson Peter Wilson Marcelo Amar Robert Shamburek Sotirios K. Karathanasis Alan T. Remaley A new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| description |
Highlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophoresis/beta-quantification in a large number of subjects. The new lipoprotein phenotyping system identifies high-risk cardiovascular patients and helps direct clinical management. A major advance is that the new lipoprotein phenotypes are based on just the standard lipid panel, and thus can be automatically calculated by the clinical laboratory and widely implemented. |
| format |
article |
| author |
Maureen Sampson Rami A. Ballout Daniel Soffer Anna Wolska Sierra Wilson Jeff Meeusen Leslie J. Donato Erica Fatica James D. Otvos Eliot A. Brinton Robert S. Rosenson Peter Wilson Marcelo Amar Robert Shamburek Sotirios K. Karathanasis Alan T. Remaley |
| author_facet |
Maureen Sampson Rami A. Ballout Daniel Soffer Anna Wolska Sierra Wilson Jeff Meeusen Leslie J. Donato Erica Fatica James D. Otvos Eliot A. Brinton Robert S. Rosenson Peter Wilson Marcelo Amar Robert Shamburek Sotirios K. Karathanasis Alan T. Remaley |
| author_sort |
Maureen Sampson |
| title |
A new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| title_short |
A new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| title_full |
A new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| title_fullStr |
A new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| title_full_unstemmed |
A new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| title_sort |
new phenotypic classification system for dyslipidemias based on the standard lipid panel |
| publisher |
BMC |
| publishDate |
2021 |
| url |
https://doaj.org/article/00d7e07ea77947e29c74d7d4034f28c2 |
| work_keys_str_mv |
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