Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics

Understanding the interaction between nanoparticles and biomolecules is crucial for improving current drug-delivery systems. Here, the authors shed light on the essential role of the surface and other physicochemical properties of a library of nanoparticles on their in vivo pharmacokinetics.

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Autores principales: Nicolas Bertrand, Philippe Grenier, Morteza Mahmoudi, Eliana M. Lima, Eric A. Appel, Flavio Dormont, Jong-Min Lim, Rohit Karnik, Robert Langer, Omid C. Farokhzad
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/00dc4fa9069d4166b50ad9376daec172
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