Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis
Plants regulate phosphate homeostasis via the interaction of PHR transcription factors with SPX receptors bound to inositol pyrophosphate signaling molecules. Here the authors show that inositol pyrophosphate-bound SPX interacts with the coiled-coil domain of PHR, which regulates the oligomerization...
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2021
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oai:doaj.org-article:00e29285b86d4975ada814bc3bd2fb9d2021-12-02T14:11:45ZInositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis10.1038/s41467-020-20681-42041-1723https://doaj.org/article/00e29285b86d4975ada814bc3bd2fb9d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20681-4https://doaj.org/toc/2041-1723Plants regulate phosphate homeostasis via the interaction of PHR transcription factors with SPX receptors bound to inositol pyrophosphate signaling molecules. Here the authors show that inositol pyrophosphate-bound SPX interacts with the coiled-coil domain of PHR, which regulates the oligomerization and activity of the transcription factor.Martina K. RiedRebekka WildJinsheng ZhuJoka PipercevicKristina SturmLarissa BrogerRobert K. HarmelLuciano A. AbriataLudwig A. HothornDorothea FiedlerSebastian HillerMichael HothornNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Martina K. Ried Rebekka Wild Jinsheng Zhu Joka Pipercevic Kristina Sturm Larissa Broger Robert K. Harmel Luciano A. Abriata Ludwig A. Hothorn Dorothea Fiedler Sebastian Hiller Michael Hothorn Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis |
description |
Plants regulate phosphate homeostasis via the interaction of PHR transcription factors with SPX receptors bound to inositol pyrophosphate signaling molecules. Here the authors show that inositol pyrophosphate-bound SPX interacts with the coiled-coil domain of PHR, which regulates the oligomerization and activity of the transcription factor. |
format |
article |
author |
Martina K. Ried Rebekka Wild Jinsheng Zhu Joka Pipercevic Kristina Sturm Larissa Broger Robert K. Harmel Luciano A. Abriata Ludwig A. Hothorn Dorothea Fiedler Sebastian Hiller Michael Hothorn |
author_facet |
Martina K. Ried Rebekka Wild Jinsheng Zhu Joka Pipercevic Kristina Sturm Larissa Broger Robert K. Harmel Luciano A. Abriata Ludwig A. Hothorn Dorothea Fiedler Sebastian Hiller Michael Hothorn |
author_sort |
Martina K. Ried |
title |
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis |
title_short |
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis |
title_full |
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis |
title_fullStr |
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis |
title_full_unstemmed |
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis |
title_sort |
inositol pyrophosphates promote the interaction of spx domains with the coiled-coil motif of phr transcription factors to regulate plant phosphate homeostasis |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/00e29285b86d4975ada814bc3bd2fb9d |
work_keys_str_mv |
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