Impact of covid-19 on mental health and aging

The potential ramifications of the COVID-19 pandemic on the population's mental health are a rising global concern. Both at the individual and community level, the erratic and uncertain COVID-19 outbreak has the prospective to exhibit a detrimental effect on psychological health and aging. At p...

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Autores principales:	Priyanka Sharma, Ramesh Sharma
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	COVID-19 SARS-CoV-2 Telomere Autophagy Antiaging drug Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/00f144e065ab49e9b0b2c8db50a03268
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spelling	oai:doaj.org-article:00f144e065ab49e9b0b2c8db50a032682021-11-20T04:56:40ZImpact of covid-19 on mental health and aging1319-562X10.1016/j.sjbs.2021.07.087https://doaj.org/article/00f144e065ab49e9b0b2c8db50a032682021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1319562X21006707https://doaj.org/toc/1319-562XThe potential ramifications of the COVID-19 pandemic on the population's mental health are a rising global concern. Both at the individual and community level, the erratic and uncertain COVID-19 outbreak has the prospective to exhibit a detrimental effect on psychological health and aging. At present, various measures are dedicated to the parameters like awareness of epidemiology, clinical aspects, mode of transmission, counteracting the spread of the infection, and public health problems, although this initiative has neglected critical mental health concerns. This study is to investigate the outbreak to study the level of harmful effects on mental health and its crosstalk with aging. Global execution of preventive, control measures and resilience establishment are challenging factors whereas reformed lifestyle such as lockdown, coping with self-isolation, quarantine, social distancing, and post-traumatic stress disorders are alarming. Hallmarks of aging which interact with each other, have been suggested to affect the healthspan in aged adults, possibly due to attenuated immunity. Among various hallmarks, we concentrated on those that show direct or indirect interaction with viral infections, comprising inflammation, genomic instability, impaired mitochondrial function, epigenetic modification, telomere attrition, and damaged autophagy. These hallmarks possibly contribute to the elicited pathophysiological responses to SARS-CoV-2 and may add an additive risk of accelerated aging post-recovery among aged adults. Here, the role of antiaging drug candidates that require main consideration in COVID-19 research is discussed briefly. In the later future, it can emerge as a potential therapeutic approach in the treatment of patients with severe infection.Priyanka SharmaRamesh SharmaElsevierarticleCOVID-19SARS-CoV-2TelomereAutophagyAntiaging drugBiology (General)QH301-705.5ENSaudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7046-7053 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 SARS-CoV-2 Telomere Autophagy Antiaging drug Biology (General) QH301-705.5
spellingShingle	COVID-19 SARS-CoV-2 Telomere Autophagy Antiaging drug Biology (General) QH301-705.5 Priyanka Sharma Ramesh Sharma Impact of covid-19 on mental health and aging
description	The potential ramifications of the COVID-19 pandemic on the population's mental health are a rising global concern. Both at the individual and community level, the erratic and uncertain COVID-19 outbreak has the prospective to exhibit a detrimental effect on psychological health and aging. At present, various measures are dedicated to the parameters like awareness of epidemiology, clinical aspects, mode of transmission, counteracting the spread of the infection, and public health problems, although this initiative has neglected critical mental health concerns. This study is to investigate the outbreak to study the level of harmful effects on mental health and its crosstalk with aging. Global execution of preventive, control measures and resilience establishment are challenging factors whereas reformed lifestyle such as lockdown, coping with self-isolation, quarantine, social distancing, and post-traumatic stress disorders are alarming. Hallmarks of aging which interact with each other, have been suggested to affect the healthspan in aged adults, possibly due to attenuated immunity. Among various hallmarks, we concentrated on those that show direct or indirect interaction with viral infections, comprising inflammation, genomic instability, impaired mitochondrial function, epigenetic modification, telomere attrition, and damaged autophagy. These hallmarks possibly contribute to the elicited pathophysiological responses to SARS-CoV-2 and may add an additive risk of accelerated aging post-recovery among aged adults. Here, the role of antiaging drug candidates that require main consideration in COVID-19 research is discussed briefly. In the later future, it can emerge as a potential therapeutic approach in the treatment of patients with severe infection.
format	article
author	Priyanka Sharma Ramesh Sharma
author_facet	Priyanka Sharma Ramesh Sharma
author_sort	Priyanka Sharma
title	Impact of covid-19 on mental health and aging
title_short	Impact of covid-19 on mental health and aging
title_full	Impact of covid-19 on mental health and aging
title_fullStr	Impact of covid-19 on mental health and aging
title_full_unstemmed	Impact of covid-19 on mental health and aging
title_sort	impact of covid-19 on mental health and aging
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/00f144e065ab49e9b0b2c8db50a03268
work_keys_str_mv	AT priyankasharma impactofcovid19onmentalhealthandaging AT rameshsharma impactofcovid19onmentalhealthandaging
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Impact of covid-19 on mental health and aging

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