Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses
Stimulator of interferon genes (STING) is known to be involved in defence against DNA viruses, but its role in the control of RNA viruses remains poorly explored. Here the authors show that STING participates in an innate immune response to RNA virus infection in a cGAS-independent manner.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/00f2e460d4a44590a591e3a422a9f087 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:00f2e460d4a44590a591e3a422a9f087 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:00f2e460d4a44590a591e3a422a9f0872021-12-02T17:33:08ZInfluenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses10.1038/ncomms106802041-1723https://doaj.org/article/00f2e460d4a44590a591e3a422a9f0872016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10680https://doaj.org/toc/2041-1723Stimulator of interferon genes (STING) is known to be involved in defence against DNA viruses, but its role in the control of RNA viruses remains poorly explored. Here the authors show that STING participates in an innate immune response to RNA virus infection in a cGAS-independent manner.Christian K. HolmStine H. RahbekHans Henrik GadRasmus O. BakMartin R. JakobsenZhaozaho JiangAnne Louise HansenSimon K. JensenChenglong SunMartin K. ThomsenAnders LaustsenCamilla G. NielsenKasper SeverinsenYingluo XiongDara L. BurdetteVeit HornungRobert Jan LebbinkMogens DuchKatherine A. FitzgeraldShervin BahramiJakob Giehm MikkelsenRune HartmannSøren R. PaludanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Christian K. Holm Stine H. Rahbek Hans Henrik Gad Rasmus O. Bak Martin R. Jakobsen Zhaozaho Jiang Anne Louise Hansen Simon K. Jensen Chenglong Sun Martin K. Thomsen Anders Laustsen Camilla G. Nielsen Kasper Severinsen Yingluo Xiong Dara L. Burdette Veit Hornung Robert Jan Lebbink Mogens Duch Katherine A. Fitzgerald Shervin Bahrami Jakob Giehm Mikkelsen Rune Hartmann Søren R. Paludan Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses |
| description |
Stimulator of interferon genes (STING) is known to be involved in defence against DNA viruses, but its role in the control of RNA viruses remains poorly explored. Here the authors show that STING participates in an innate immune response to RNA virus infection in a cGAS-independent manner. |
| format |
article |
| author |
Christian K. Holm Stine H. Rahbek Hans Henrik Gad Rasmus O. Bak Martin R. Jakobsen Zhaozaho Jiang Anne Louise Hansen Simon K. Jensen Chenglong Sun Martin K. Thomsen Anders Laustsen Camilla G. Nielsen Kasper Severinsen Yingluo Xiong Dara L. Burdette Veit Hornung Robert Jan Lebbink Mogens Duch Katherine A. Fitzgerald Shervin Bahrami Jakob Giehm Mikkelsen Rune Hartmann Søren R. Paludan |
| author_facet |
Christian K. Holm Stine H. Rahbek Hans Henrik Gad Rasmus O. Bak Martin R. Jakobsen Zhaozaho Jiang Anne Louise Hansen Simon K. Jensen Chenglong Sun Martin K. Thomsen Anders Laustsen Camilla G. Nielsen Kasper Severinsen Yingluo Xiong Dara L. Burdette Veit Hornung Robert Jan Lebbink Mogens Duch Katherine A. Fitzgerald Shervin Bahrami Jakob Giehm Mikkelsen Rune Hartmann Søren R. Paludan |
| author_sort |
Christian K. Holm |
| title |
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses |
| title_short |
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses |
| title_full |
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses |
| title_fullStr |
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses |
| title_full_unstemmed |
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses |
| title_sort |
influenza a virus targets a cgas-independent sting pathway that controls enveloped rna viruses |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/00f2e460d4a44590a591e3a422a9f087 |
| work_keys_str_mv |
AT christiankholm influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT stinehrahbek influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT hanshenrikgad influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT rasmusobak influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT martinrjakobsen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT zhaozahojiang influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT annelouisehansen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT simonkjensen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT chenglongsun influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT martinkthomsen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT anderslaustsen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT camillagnielsen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT kasperseverinsen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT yingluoxiong influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT daralburdette influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT veithornung influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT robertjanlebbink influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT mogensduch influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT katherineafitzgerald influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT shervinbahrami influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT jakobgiehmmikkelsen influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT runehartmann influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses AT sørenrpaludan influenzaavirustargetsacgasindependentstingpathwaythatcontrolsenvelopedrnaviruses |
| _version_ |
1718380039908622336 |