Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status

As the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is a new virus, the current knowledge on the immunopathogenesis of this newly emerged SARS-CoV-2 is beginning to unravel with intensive ongoing global research efforts. Although a plethora of new studies have been published in a short...

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Autores principales:	Nitin Saksena, Srinivasa Reddy Bonam, Monica Miranda-Saksena
Formato:	article
Lenguaje:	EN
Publicado:	Open Exploration Publishing Inc. 2021
Materias:	coronavirus disease 2019 severe acute respiratory syndrome coronavirus 2 immunopathology viral infection acute respiratory distress syndrome cytokine storm immunopathogenesis Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/00f37e9b255e43e9aaf649e40513bef4
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spelling	oai:doaj.org-article:00f37e9b255e43e9aaf649e40513bef42021-11-24T01:48:34ZImmunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status10.37349/ei.2021.000072768-6655https://doaj.org/article/00f37e9b255e43e9aaf649e40513bef42021-06-01T00:00:00Zhttps://www.explorationpub.com/Journals/ei/Article/10037https://doaj.org/toc/2768-6655As the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is a new virus, the current knowledge on the immunopathogenesis of this newly emerged SARS-CoV-2 is beginning to unravel with intensive ongoing global research efforts. Although a plethora of new studies have been published in a short space of time describing how the virus causes disease and incurs insults on the host immune system and the underlying immunopathogenic mechanisms remain to be elucidated. Thus, the discussion in this review is based on the most current knowledge on the immunopathogenesis of SARS-CoV-2 that has emerged in the past 12 months. The main objective is to shed light on the most current concepts in immunopathological aspects of the lung, bloodstream, and brain caused by the SARS-CoV-2, which has led to the current pandemic resulting in > 100 million infections and > 2 million deaths, and ongoing.Nitin SaksenaSrinivasa Reddy BonamMonica Miranda-SaksenaOpen Exploration Publishing Inc.articlecoronavirus disease 2019severe acute respiratory syndrome coronavirus 2immunopathologyviral infectionacute respiratory distress syndromecytokine stormimmunopathogenesisImmunologic diseases. AllergyRC581-607ENExploration of Immunology, Vol 1, Iss 1, Pp 61-79 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	coronavirus disease 2019 severe acute respiratory syndrome coronavirus 2 immunopathology viral infection acute respiratory distress syndrome cytokine storm immunopathogenesis Immunologic diseases. Allergy RC581-607
spellingShingle	coronavirus disease 2019 severe acute respiratory syndrome coronavirus 2 immunopathology viral infection acute respiratory distress syndrome cytokine storm immunopathogenesis Immunologic diseases. Allergy RC581-607 Nitin Saksena Srinivasa Reddy Bonam Monica Miranda-Saksena Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
description	As the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is a new virus, the current knowledge on the immunopathogenesis of this newly emerged SARS-CoV-2 is beginning to unravel with intensive ongoing global research efforts. Although a plethora of new studies have been published in a short space of time describing how the virus causes disease and incurs insults on the host immune system and the underlying immunopathogenic mechanisms remain to be elucidated. Thus, the discussion in this review is based on the most current knowledge on the immunopathogenesis of SARS-CoV-2 that has emerged in the past 12 months. The main objective is to shed light on the most current concepts in immunopathological aspects of the lung, bloodstream, and brain caused by the SARS-CoV-2, which has led to the current pandemic resulting in > 100 million infections and > 2 million deaths, and ongoing.
format	article
author	Nitin Saksena Srinivasa Reddy Bonam Monica Miranda-Saksena
author_facet	Nitin Saksena Srinivasa Reddy Bonam Monica Miranda-Saksena
author_sort	Nitin Saksena
title	Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
title_short	Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
title_full	Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
title_fullStr	Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
title_full_unstemmed	Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
title_sort	immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
publisher	Open Exploration Publishing Inc.
publishDate	2021
url	https://doaj.org/article/00f37e9b255e43e9aaf649e40513bef4
work_keys_str_mv	AT nitinsaksena immunopathogenesisofsevereacuterespiratorysyndromecoronavirus2evolvingknowledgeanditscurrentstatus AT srinivasareddybonam immunopathogenesisofsevereacuterespiratorysyndromecoronavirus2evolvingknowledgeanditscurrentstatus AT monicamirandasaksena immunopathogenesisofsevereacuterespiratorysyndromecoronavirus2evolvingknowledgeanditscurrentstatus
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Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status

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