Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats

Objective. Early life stress influences the development of metabolic disorders, including functional changes in the developing of pancreas mediated hypothalamic-pituitary-adrenal (HPA) axis. In the present study, the role of an early postnatal stress on corticosterone, glucose, and insulin levels wa...

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Autores principales: Sadeghimahalli Forouzan, Zardooz Homeira, Golchoobian Ravieh
Formato: article
Lenguaje:EN
Publicado: Sciendo 2019
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Acceso en línea:https://doaj.org/article/00f657c54727412e880c93793c1213e4
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spelling oai:doaj.org-article:00f657c54727412e880c93793c1213e42021-12-02T16:40:25ZEarly postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats1336-032910.2478/enr-2019-0021https://doaj.org/article/00f657c54727412e880c93793c1213e42019-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0021https://doaj.org/toc/1336-0329Objective. Early life stress influences the development of metabolic disorders, including functional changes in the developing of pancreas mediated hypothalamic-pituitary-adrenal (HPA) axis. In the present study, the role of an early postnatal stress on corticosterone, glucose, and insulin levels was investigated during young adulthood.Sadeghimahalli ForouzanZardooz HomeiraGolchoobian RaviehSciendoarticlepsychological stressinsulin sensitivityadultcorticosteronehpa axisDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 4, Pp 213-220 (2019)
institution DOAJ
collection DOAJ
language EN
topic psychological stress
insulin sensitivity
adult
corticosterone
hpa axis
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle psychological stress
insulin sensitivity
adult
corticosterone
hpa axis
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Sadeghimahalli Forouzan
Zardooz Homeira
Golchoobian Ravieh
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
description Objective. Early life stress influences the development of metabolic disorders, including functional changes in the developing of pancreas mediated hypothalamic-pituitary-adrenal (HPA) axis. In the present study, the role of an early postnatal stress on corticosterone, glucose, and insulin levels was investigated during young adulthood.
format article
author Sadeghimahalli Forouzan
Zardooz Homeira
Golchoobian Ravieh
author_facet Sadeghimahalli Forouzan
Zardooz Homeira
Golchoobian Ravieh
author_sort Sadeghimahalli Forouzan
title Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
title_short Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
title_full Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
title_fullStr Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
title_full_unstemmed Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
title_sort early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
publisher Sciendo
publishDate 2019
url https://doaj.org/article/00f657c54727412e880c93793c1213e4
work_keys_str_mv AT sadeghimahalliforouzan earlypostnatalhypothalamicpituitaryadrenalaxisactivityandreducedinsulinsensitivityinadultrats
AT zardoozhomeira earlypostnatalhypothalamicpituitaryadrenalaxisactivityandreducedinsulinsensitivityinadultrats
AT golchoobianravieh earlypostnatalhypothalamicpituitaryadrenalaxisactivityandreducedinsulinsensitivityinadultrats
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