Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats
Objective. Early life stress influences the development of metabolic disorders, including functional changes in the developing of pancreas mediated hypothalamic-pituitary-adrenal (HPA) axis. In the present study, the role of an early postnatal stress on corticosterone, glucose, and insulin levels wa...
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oai:doaj.org-article:00f657c54727412e880c93793c1213e42021-12-02T16:40:25ZEarly postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats1336-032910.2478/enr-2019-0021https://doaj.org/article/00f657c54727412e880c93793c1213e42019-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0021https://doaj.org/toc/1336-0329Objective. Early life stress influences the development of metabolic disorders, including functional changes in the developing of pancreas mediated hypothalamic-pituitary-adrenal (HPA) axis. In the present study, the role of an early postnatal stress on corticosterone, glucose, and insulin levels was investigated during young adulthood.Sadeghimahalli ForouzanZardooz HomeiraGolchoobian RaviehSciendoarticlepsychological stressinsulin sensitivityadultcorticosteronehpa axisDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 4, Pp 213-220 (2019) |
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DOAJ |
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psychological stress insulin sensitivity adult corticosterone hpa axis Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
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psychological stress insulin sensitivity adult corticosterone hpa axis Diseases of the endocrine glands. Clinical endocrinology RC648-665 Sadeghimahalli Forouzan Zardooz Homeira Golchoobian Ravieh Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
description |
Objective. Early life stress influences the development of metabolic disorders, including functional changes in the developing of pancreas mediated hypothalamic-pituitary-adrenal (HPA) axis. In the present study, the role of an early postnatal stress on corticosterone, glucose, and insulin levels was investigated during young adulthood. |
format |
article |
author |
Sadeghimahalli Forouzan Zardooz Homeira Golchoobian Ravieh |
author_facet |
Sadeghimahalli Forouzan Zardooz Homeira Golchoobian Ravieh |
author_sort |
Sadeghimahalli Forouzan |
title |
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
title_short |
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
title_full |
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
title_fullStr |
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
title_full_unstemmed |
Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
title_sort |
early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats |
publisher |
Sciendo |
publishDate |
2019 |
url |
https://doaj.org/article/00f657c54727412e880c93793c1213e4 |
work_keys_str_mv |
AT sadeghimahalliforouzan earlypostnatalhypothalamicpituitaryadrenalaxisactivityandreducedinsulinsensitivityinadultrats AT zardoozhomeira earlypostnatalhypothalamicpituitaryadrenalaxisactivityandreducedinsulinsensitivityinadultrats AT golchoobianravieh earlypostnatalhypothalamicpituitaryadrenalaxisactivityandreducedinsulinsensitivityinadultrats |
_version_ |
1718383553037729792 |