Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS

Hydrogen can be used to reduce the concentration of reactive oxygen species (ROS), but its delivery to diseased tissues is challenging due to its low solubility. Here the authors develop a photosynthesis-inspired FRET nanocomplex to detect and scavenge local excess of ROS in the tissue using photoca...

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Autores principales: Wei-Lin Wan, Bo Tian, Yu-Jung Lin, Chiranjeevi Korupalli, Ming-Yen Lu, Qinghua Cui, Dehui Wan, Yen Chang, Hsing-Wen Sung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0101c2f5b95943e9bf3120cf67710919
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spelling oai:doaj.org-article:0101c2f5b95943e9bf3120cf677109192021-12-02T16:56:33ZPhotosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS10.1038/s41467-020-14413-x2041-1723https://doaj.org/article/0101c2f5b95943e9bf3120cf677109192020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14413-xhttps://doaj.org/toc/2041-1723Hydrogen can be used to reduce the concentration of reactive oxygen species (ROS), but its delivery to diseased tissues is challenging due to its low solubility. Here the authors develop a photosynthesis-inspired FRET nanocomplex to detect and scavenge local excess of ROS in the tissue using photocatalytic hydrogen production.Wei-Lin WanBo TianYu-Jung LinChiranjeevi KorupalliMing-Yen LuQinghua CuiDehui WanYen ChangHsing-Wen SungNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wei-Lin Wan
Bo Tian
Yu-Jung Lin
Chiranjeevi Korupalli
Ming-Yen Lu
Qinghua Cui
Dehui Wan
Yen Chang
Hsing-Wen Sung
Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS
description Hydrogen can be used to reduce the concentration of reactive oxygen species (ROS), but its delivery to diseased tissues is challenging due to its low solubility. Here the authors develop a photosynthesis-inspired FRET nanocomplex to detect and scavenge local excess of ROS in the tissue using photocatalytic hydrogen production.
format article
author Wei-Lin Wan
Bo Tian
Yu-Jung Lin
Chiranjeevi Korupalli
Ming-Yen Lu
Qinghua Cui
Dehui Wan
Yen Chang
Hsing-Wen Sung
author_facet Wei-Lin Wan
Bo Tian
Yu-Jung Lin
Chiranjeevi Korupalli
Ming-Yen Lu
Qinghua Cui
Dehui Wan
Yen Chang
Hsing-Wen Sung
author_sort Wei-Lin Wan
title Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS
title_short Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS
title_full Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS
title_fullStr Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS
title_full_unstemmed Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS
title_sort photosynthesis-inspired h2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ros
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/0101c2f5b95943e9bf3120cf67710919
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