Antibody response against selected epitopes in the HIV-1 envelope gp41 ectodomain contributes to reduce viral burden in HIV-1 infected patients

Antibody response against selected epitopes in the HIV-1 envelope gp41 ectodomain contributes to reduce viral burden in HIV-1 infected patients

Abstract The ectodomain of gp41 is the target of potent binding and neutralizing antibodies (NAbs) and is being explored in new strategies for antibody-based HIV vaccines. Previous studies have suggested that the W164A-3S (3S) and EC26-2A4 (EC26) peptides located in the gp41 ectodomain may be potent...

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Autores principales: Rute Marcelino, Filipa Gramacho, Francisco Martin, Pedro Brogueira, Nuno Janeiro, Claudia Afonso, Robert Badura, Emília Valadas, Kamal Mansinho, Luís Caldeira, Nuno Taveira, José M. Marcelino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0102da4ba8d348b58abf91d126847f8a
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