Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury
Myeloid differentiation factor 88 (MyD88) is a hub protein in the Toll-like receptor signaling pathway, which acts as a master switch for numerous inflammatory diseases, including acute lung injury (ALI). Although this protein is considered as a crucial therapeutic target, there are currently no cli...
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Autores principales: | Jiali Song, Daoxing Chen, Yingqiao Pan, Xueqin Shi, Qian Liu, Xiaoyao Lu, Ximing Xu, Gaozhi Chen, Yuepiao Cai |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/01110403e2684410949b998f88545cb3 |
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