Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury

Myeloid differentiation factor 88 (MyD88) is a hub protein in the Toll-like receptor signaling pathway, which acts as a master switch for numerous inflammatory diseases, including acute lung injury (ALI). Although this protein is considered as a crucial therapeutic target, there are currently no cli...

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Autores principales: Jiali Song, Daoxing Chen, Yingqiao Pan, Xueqin Shi, Qian Liu, Xiaoyao Lu, Ximing Xu, Gaozhi Chen, Yuepiao Cai
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/01110403e2684410949b998f88545cb3
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