Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience

Introduction: Extracorporeal Membrane Oxygenation (ECMO) is a lifesaving procedure for patients with refractory cardiac or respiratory failure. The indications for ECMO are growing, and it is increasingly being used to support cardiopulmonary failure in children. However, the risks and benefits of E...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wirapatra Iamwat, Piya Samankatiwat, Rojjanee Lertbunrian, Nattachai Anantasit
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	extracorporeal membrane oxygenation pediatric risk factors outcome neonatal Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/0111ded33dc14a44bcaa47ea129eb5f6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0111ded33dc14a44bcaa47ea129eb5f6
record_format	dspace
spelling	oai:doaj.org-article:0111ded33dc14a44bcaa47ea129eb5f62021-11-16T06:47:10ZClinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience2296-236010.3389/fped.2021.753708https://doaj.org/article/0111ded33dc14a44bcaa47ea129eb5f62021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fped.2021.753708/fullhttps://doaj.org/toc/2296-2360Introduction: Extracorporeal Membrane Oxygenation (ECMO) is a lifesaving procedure for patients with refractory cardiac or respiratory failure. The indications for ECMO are growing, and it is increasingly being used to support cardiopulmonary failure in children. However, the risks and benefits of ECMO should be weighed before deploying it on the patients. The objectives of this study were to identify the mortality risk factors and to determine the ECMO outcomes.Methods: The retrospective chart reviews were done for all patients aged 1 day−20 years old receiving ECMO between January 2010 and December 2020.Results: Seventy patients were enrolled in the study. The median age was 31.3 months. The incidence of VA and VV ECMO was 85.7 and 14.3%, respectively. The most common indication for ECMO was the failure to wean off cardiopulmonary bypass after cardiac surgery. Pre-existing acute kidney injury (OR 4.23; 95% CI 1.34–13.32, p = 0.014) and delayed enteral feeding (OR 3.85, 95% CI 1.23–12.02, p = 0.020), and coagulopathy (OD 12.64; 95% CI 1.13–141.13, p = 0.039) were associated with the higher rate of mortality. The rates of ECMO survival and survival to discharge were 70 and 50%, respectively.Conclusion: ECMO is the lifesaving tool for critically ill pediatric patients. Pre-existing acute kidney injury, delayed enteral feeding, and coagulopathy were the potential risk factors associated with poor outcomes in children receiving ECMO. However, ECMO setup can be done successfully in a developing country.Wirapatra IamwatPiya SamankatiwatRojjanee LertbunrianNattachai AnantasitFrontiers Media S.A.articleextracorporeal membrane oxygenationpediatricrisk factorsoutcomeneonatalPediatricsRJ1-570ENFrontiers in Pediatrics, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	extracorporeal membrane oxygenation pediatric risk factors outcome neonatal Pediatrics RJ1-570
spellingShingle	extracorporeal membrane oxygenation pediatric risk factors outcome neonatal Pediatrics RJ1-570 Wirapatra Iamwat Piya Samankatiwat Rojjanee Lertbunrian Nattachai Anantasit Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience
description	Introduction: Extracorporeal Membrane Oxygenation (ECMO) is a lifesaving procedure for patients with refractory cardiac or respiratory failure. The indications for ECMO are growing, and it is increasingly being used to support cardiopulmonary failure in children. However, the risks and benefits of ECMO should be weighed before deploying it on the patients. The objectives of this study were to identify the mortality risk factors and to determine the ECMO outcomes.Methods: The retrospective chart reviews were done for all patients aged 1 day−20 years old receiving ECMO between January 2010 and December 2020.Results: Seventy patients were enrolled in the study. The median age was 31.3 months. The incidence of VA and VV ECMO was 85.7 and 14.3%, respectively. The most common indication for ECMO was the failure to wean off cardiopulmonary bypass after cardiac surgery. Pre-existing acute kidney injury (OR 4.23; 95% CI 1.34–13.32, p = 0.014) and delayed enteral feeding (OR 3.85, 95% CI 1.23–12.02, p = 0.020), and coagulopathy (OD 12.64; 95% CI 1.13–141.13, p = 0.039) were associated with the higher rate of mortality. The rates of ECMO survival and survival to discharge were 70 and 50%, respectively.Conclusion: ECMO is the lifesaving tool for critically ill pediatric patients. Pre-existing acute kidney injury, delayed enteral feeding, and coagulopathy were the potential risk factors associated with poor outcomes in children receiving ECMO. However, ECMO setup can be done successfully in a developing country.
format	article
author	Wirapatra Iamwat Piya Samankatiwat Rojjanee Lertbunrian Nattachai Anantasit
author_facet	Wirapatra Iamwat Piya Samankatiwat Rojjanee Lertbunrian Nattachai Anantasit
author_sort	Wirapatra Iamwat
title	Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience
title_short	Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience
title_full	Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience
title_fullStr	Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience
title_full_unstemmed	Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience
title_sort	clinical characteristics and outcomes of children with extracorporeal membrane oxygenation in a developing country: an 11-year single-center experience
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/0111ded33dc14a44bcaa47ea129eb5f6
work_keys_str_mv	AT wirapatraiamwat clinicalcharacteristicsandoutcomesofchildrenwithextracorporealmembraneoxygenationinadevelopingcountryan11yearsinglecenterexperience AT piyasamankatiwat clinicalcharacteristicsandoutcomesofchildrenwithextracorporealmembraneoxygenationinadevelopingcountryan11yearsinglecenterexperience AT rojjaneelertbunrian clinicalcharacteristicsandoutcomesofchildrenwithextracorporealmembraneoxygenationinadevelopingcountryan11yearsinglecenterexperience AT nattachaianantasit clinicalcharacteristicsandoutcomesofchildrenwithextracorporealmembraneoxygenationinadevelopingcountryan11yearsinglecenterexperience
_version_	1718426644243283968

Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience

Ejemplares similares