Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanis...
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Scientific Сentre for Family Health and Human Reproduction Problems
2015
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oai:doaj.org-article:011ab3f869014506bab10198c310c5662021-11-23T06:14:33ZMetabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes2541-94202587-9596https://doaj.org/article/011ab3f869014506bab10198c310c5662015-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/130https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanisms and researching the methods for its correction. 51 male athletes of 22,1 ± 3,7 y. o. and 64 healthy males of the same age as the reference group were participated in the study. We found that metabolic resources providing the intensity of respiratory burst depend on mitochondrial processes condition and lipid metabolism. The activation index has logarithmic dependence on NAD(P)-MDH, NAD-MDH, NAD-IDH activities. Therefore the functional activity of neutrophilic granulocytes in athletes has positive correlation with plastic exchange level and negative correlation with oxygen-depended ATP production.K. P. BazarinA. A. SavchenkoI. I. GvozdevScientific Сentre for Family Health and Human Reproduction Problemsarticleneutrophilic granulocytesmetabolismfunctional activityhigh physical loadScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 7-10 (2015) |
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neutrophilic granulocytes metabolism functional activity high physical load Science Q |
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neutrophilic granulocytes metabolism functional activity high physical load Science Q K. P. Bazarin A. A. Savchenko I. I. Gvozdev Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
description |
The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanisms and researching the methods for its correction. 51 male athletes of 22,1 ± 3,7 y. o. and 64 healthy males of the same age as the reference group were participated in the study. We found that metabolic resources providing the intensity of respiratory burst depend on mitochondrial processes condition and lipid metabolism. The activation index has logarithmic dependence on NAD(P)-MDH, NAD-MDH, NAD-IDH activities. Therefore the functional activity of neutrophilic granulocytes in athletes has positive correlation with plastic exchange level and negative correlation with oxygen-depended ATP production. |
format |
article |
author |
K. P. Bazarin A. A. Savchenko I. I. Gvozdev |
author_facet |
K. P. Bazarin A. A. Savchenko I. I. Gvozdev |
author_sort |
K. P. Bazarin |
title |
Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
title_short |
Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
title_full |
Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
title_fullStr |
Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
title_full_unstemmed |
Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
title_sort |
metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2015 |
url |
https://doaj.org/article/011ab3f869014506bab10198c310c566 |
work_keys_str_mv |
AT kpbazarin metabolicmechanismsofchemiluminescentactivityofneutrophilicgranulocytesinqualifiedathletes AT aasavchenko metabolicmechanismsofchemiluminescentactivityofneutrophilicgranulocytesinqualifiedathletes AT iigvozdev metabolicmechanismsofchemiluminescentactivityofneutrophilicgranulocytesinqualifiedathletes |
_version_ |
1718417049771835392 |