Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes

The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanis...

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Autores principales: K. P. Bazarin, A. A. Savchenko, I. I. Gvozdev
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2015
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Acceso en línea:https://doaj.org/article/011ab3f869014506bab10198c310c566
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spelling oai:doaj.org-article:011ab3f869014506bab10198c310c5662021-11-23T06:14:33ZMetabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes2541-94202587-9596https://doaj.org/article/011ab3f869014506bab10198c310c5662015-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/130https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanisms and researching the methods for its correction. 51 male athletes of 22,1 ± 3,7 y. o. and 64 healthy males of the same age as the reference group were participated in the study. We found that metabolic resources providing the intensity of respiratory burst depend on mitochondrial processes condition and lipid metabolism. The activation index has logarithmic dependence on NAD(P)-MDH, NAD-MDH, NAD-IDH activities. Therefore the functional activity of neutrophilic granulocytes in athletes has positive correlation with plastic exchange level and negative correlation with oxygen-depended ATP production.K. P. BazarinA. A. SavchenkoI. I. GvozdevScientific Сentre for Family Health and Human Reproduction Problemsarticleneutrophilic granulocytesmetabolismfunctional activityhigh physical loadScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 7-10 (2015)
institution DOAJ
collection DOAJ
language RU
topic neutrophilic granulocytes
metabolism
functional activity
high physical load
Science
Q
spellingShingle neutrophilic granulocytes
metabolism
functional activity
high physical load
Science
Q
K. P. Bazarin
A. A. Savchenko
I. I. Gvozdev
Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
description The high exercise stress in sport causes the decrease of immune cells reactivity. Studying the interrelation between hemiluminscent activity of neutrophylic granulocytes and NAD(P)-depending dehydrogenases in athletes is important for better understanding of sport immunodeficiency metabolic mechanisms and researching the methods for its correction. 51 male athletes of 22,1 ± 3,7 y. o. and 64 healthy males of the same age as the reference group were participated in the study. We found that metabolic resources providing the intensity of respiratory burst depend on mitochondrial processes condition and lipid metabolism. The activation index has logarithmic dependence on NAD(P)-MDH, NAD-MDH, NAD-IDH activities. Therefore the functional activity of neutrophilic granulocytes in athletes has positive correlation with plastic exchange level and negative correlation with oxygen-depended ATP production.
format article
author K. P. Bazarin
A. A. Savchenko
I. I. Gvozdev
author_facet K. P. Bazarin
A. A. Savchenko
I. I. Gvozdev
author_sort K. P. Bazarin
title Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
title_short Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
title_full Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
title_fullStr Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
title_full_unstemmed Metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
title_sort metabolic mechanisms of chemiluminescent activity of neutrophilic granulocytes in qualified athletes
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2015
url https://doaj.org/article/011ab3f869014506bab10198c310c566
work_keys_str_mv AT kpbazarin metabolicmechanismsofchemiluminescentactivityofneutrophilicgranulocytesinqualifiedathletes
AT aasavchenko metabolicmechanismsofchemiluminescentactivityofneutrophilicgranulocytesinqualifiedathletes
AT iigvozdev metabolicmechanismsofchemiluminescentactivityofneutrophilicgranulocytesinqualifiedathletes
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