Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein

ABSTRACT The widely conserved LytR-CpsA-Psr (LCP) family of enzymes in Gram-positive bacteria is known to attach glycopolymers, including wall teichoic acid, to the cell envelope. However, it is undetermined if these enzymes are capable of catalyzing glycan attachment to surface proteins. In the act...

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Bibliographic Details
Main Authors: Sara D. Siegel, Brendan R. Amer, Chenggang Wu, Michael R. Sawaya, Jason E. Gosschalk, Robert T. Clubb, Hung Ton-That
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
LCP
Online Access:https://doaj.org/article/012fcfa94d5c4b6d879eedef1c81d734
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