The effect of X-linked dosage compensation on complex trait variation
Dosage compensation (DC) on the X chromosome has predictable effects on genetic and phenotypic trait variance. Here, the authors use information for 20 quantitative traits in the UK Biobank and across-tissue gene expression to compare X-linked heritability and the effects of trait-associated SNPs be...
Enregistré dans:
| Auteurs principaux: | Julia Sidorenko, Irfahan Kassam, Kathryn E. Kemper, Jian Zeng, Luke R. Lloyd-Jones, Grant W. Montgomery, Greg Gibson, Andres Metspalu, Tonu Esko, Jian Yang, Allan F. McRae, Peter M. Visscher |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/013d3c416c61462f8755c27f7c64fc0a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Improved polygenic prediction by Bayesian multiple regression on summary statistics
par: Luke R. Lloyd-Jones, et autres
Publié: (2019) -
Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits
par: Yang Wu, et autres
Publié: (2018) -
Transcriptional regulation of dosage compensation in Carica papaya
par: Juan Liu, et autres
Publié: (2021) -
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
par: Ting Qi, et autres
Publié: (2018) -
Mechanisms and evolutionary patterns of mammalian and avian dosage compensation.
par: Philippe Julien, et autres
Publié: (2012)