Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route

The emerging science of nanotechnology sparked a research attention in its potential benefits in comparison to the conventional materials used. Oral products prepared via nanoparticles (NPs) have garnered great interest worldwide. They are used commonly to incorporate nutrients and provide antimicro...

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Autores principales:	Farzaneh Lotfipour, Shahriar Shahi, Afsaneh Farjami, Sara Salatin, Mohammad Mahmoudian, Solmaz Maleki Dizaj
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/013f82294e0c42efb1a3611a33815b50
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spelling	oai:doaj.org-article:013f82294e0c42efb1a3611a33815b502021-11-08T02:36:18ZSafety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route2314-614110.1155/2021/9322282https://doaj.org/article/013f82294e0c42efb1a3611a33815b502021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9322282https://doaj.org/toc/2314-6141The emerging science of nanotechnology sparked a research attention in its potential benefits in comparison to the conventional materials used. Oral products prepared via nanoparticles (NPs) have garnered great interest worldwide. They are used commonly to incorporate nutrients and provide antimicrobial activity. Formulation into NPs can offer opportunities for targeted drug delivery, improve drug stability in the harsh environment of the gastrointestinal (GI) tract, increase drug solubility and bioavailability, and provide sustained release in the GI tract. However, some issues like the management of toxicity and safe handling of NPs are still debated and should be well concerned before their application in oral preparations. This article will help the reader to understand safety issues of NPs in oral drug delivery and provides some recommendations to the use of NPs in the drug industry.Farzaneh LotfipourShahriar ShahiAfsaneh FarjamiSara SalatinMohammad MahmoudianSolmaz Maleki DizajHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Farzaneh Lotfipour Shahriar Shahi Afsaneh Farjami Sara Salatin Mohammad Mahmoudian Solmaz Maleki Dizaj Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
description	The emerging science of nanotechnology sparked a research attention in its potential benefits in comparison to the conventional materials used. Oral products prepared via nanoparticles (NPs) have garnered great interest worldwide. They are used commonly to incorporate nutrients and provide antimicrobial activity. Formulation into NPs can offer opportunities for targeted drug delivery, improve drug stability in the harsh environment of the gastrointestinal (GI) tract, increase drug solubility and bioavailability, and provide sustained release in the GI tract. However, some issues like the management of toxicity and safe handling of NPs are still debated and should be well concerned before their application in oral preparations. This article will help the reader to understand safety issues of NPs in oral drug delivery and provides some recommendations to the use of NPs in the drug industry.
format	article
author	Farzaneh Lotfipour Shahriar Shahi Afsaneh Farjami Sara Salatin Mohammad Mahmoudian Solmaz Maleki Dizaj
author_facet	Farzaneh Lotfipour Shahriar Shahi Afsaneh Farjami Sara Salatin Mohammad Mahmoudian Solmaz Maleki Dizaj
author_sort	Farzaneh Lotfipour
title	Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
title_short	Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
title_full	Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
title_fullStr	Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
title_full_unstemmed	Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
title_sort	safety and toxicity issues of therapeutically used nanoparticles from the oral route
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/013f82294e0c42efb1a3611a33815b50
work_keys_str_mv	AT farzanehlotfipour safetyandtoxicityissuesoftherapeuticallyusednanoparticlesfromtheoralroute AT shahriarshahi safetyandtoxicityissuesoftherapeuticallyusednanoparticlesfromtheoralroute AT afsanehfarjami safetyandtoxicityissuesoftherapeuticallyusednanoparticlesfromtheoralroute AT sarasalatin safetyandtoxicityissuesoftherapeuticallyusednanoparticlesfromtheoralroute AT mohammadmahmoudian safetyandtoxicityissuesoftherapeuticallyusednanoparticlesfromtheoralroute AT solmazmalekidizaj safetyandtoxicityissuesoftherapeuticallyusednanoparticlesfromtheoralroute
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Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route

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