Gis1 and Rph1 regulate glycerol and acetate metabolism in glucose depleted yeast cells.

Gis1 and Rph1 regulate glycerol and acetate metabolism in glucose depleted yeast cells.

Aging in organisms as diverse as yeast, nematodes, and mammals is delayed by caloric restriction, an effect mediated by the nutrient sensing TOR, RAS/cAMP, and AKT/Sch9 pathways. The transcription factor Gis1 functions downstream of these pathways in extending the lifespan of nutrient restricted yea...

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Autores principales: Jakub Orzechowski Westholm, Susanna Tronnersjö, Niklas Nordberg, Ida Olsson, Jan Komorowski, Hans Ronne
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/01445a9169cc42c5a7c83deb59272869
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