Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1

hnRNP A1 is an auxiliary factor that promotes the Microprocessor-mediated processing of pri-mir-18a, of the oncomiR-1 cluster. Here the authors employ an integrative structural biology approach and provide insights into the molecular mechanism of how hnRNP A1 facilitates pri-mir-18a biogenesis.

Guardado en:

Detalles Bibliográficos
Autores principales:	Hamed Kooshapur, Nila Roy Choudhury, Bernd Simon, Max Mühlbauer, Alexander Jussupow, Noemi Fernandez, Alisha N. Jones, Andre Dallmann, Frank Gabel, Carlo Camilloni, Gracjan Michlewski, Javier F. Caceres, Michael Sattler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/014a6dc8990b44dca7c25370f4266456
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:014a6dc8990b44dca7c25370f4266456
record_format	dspace
spelling	oai:doaj.org-article:014a6dc8990b44dca7c25370f42664562021-12-02T14:41:27ZStructural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A110.1038/s41467-018-04871-92041-1723https://doaj.org/article/014a6dc8990b44dca7c25370f42664562018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04871-9https://doaj.org/toc/2041-1723hnRNP A1 is an auxiliary factor that promotes the Microprocessor-mediated processing of pri-mir-18a, of the oncomiR-1 cluster. Here the authors employ an integrative structural biology approach and provide insights into the molecular mechanism of how hnRNP A1 facilitates pri-mir-18a biogenesis.Hamed KooshapurNila Roy ChoudhuryBernd SimonMax MühlbauerAlexander JussupowNoemi FernandezAlisha N. JonesAndre DallmannFrank GabelCarlo CamilloniGracjan MichlewskiJavier F. CaceresMichael SattlerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hamed Kooshapur Nila Roy Choudhury Bernd Simon Max Mühlbauer Alexander Jussupow Noemi Fernandez Alisha N. Jones Andre Dallmann Frank Gabel Carlo Camilloni Gracjan Michlewski Javier F. Caceres Michael Sattler Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
description	hnRNP A1 is an auxiliary factor that promotes the Microprocessor-mediated processing of pri-mir-18a, of the oncomiR-1 cluster. Here the authors employ an integrative structural biology approach and provide insights into the molecular mechanism of how hnRNP A1 facilitates pri-mir-18a biogenesis.
format	article
author	Hamed Kooshapur Nila Roy Choudhury Bernd Simon Max Mühlbauer Alexander Jussupow Noemi Fernandez Alisha N. Jones Andre Dallmann Frank Gabel Carlo Camilloni Gracjan Michlewski Javier F. Caceres Michael Sattler
author_facet	Hamed Kooshapur Nila Roy Choudhury Bernd Simon Max Mühlbauer Alexander Jussupow Noemi Fernandez Alisha N. Jones Andre Dallmann Frank Gabel Carlo Camilloni Gracjan Michlewski Javier F. Caceres Michael Sattler
author_sort	Hamed Kooshapur
title	Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
title_short	Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
title_full	Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
title_fullStr	Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
title_full_unstemmed	Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
title_sort	structural basis for terminal loop recognition and stimulation of pri-mirna-18a processing by hnrnp a1
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/014a6dc8990b44dca7c25370f4266456
work_keys_str_mv	AT hamedkooshapur structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT nilaroychoudhury structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT berndsimon structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT maxmuhlbauer structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT alexanderjussupow structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT noemifernandez structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT alishanjones structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT andredallmann structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT frankgabel structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT carlocamilloni structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT gracjanmichlewski structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT javierfcaceres structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1 AT michaelsattler structuralbasisforterminallooprecognitionandstimulationofprimirna18aprocessingbyhnrnpa1
_version_	1718389851124924416

Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1

Ejemplares similares