PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex
PWWP2A is a chromatin-binding transcriptional regulator that mediates mitosis-progression. Here, the authors provide evidence that PWWP2A directly interacts with H2A.Z nucleosomes, DNA and H3K36me3, binds to an MTA1-specific subcomplex of the NuRD complex (M1HR) and promotes changes to histone acety...
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Nature Portfolio
2018
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oai:doaj.org-article:014b47e5311d4e1aa8fa73d95eb91cdd2021-12-02T17:32:31ZPWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex10.1038/s41467-018-06665-52041-1723https://doaj.org/article/014b47e5311d4e1aa8fa73d95eb91cdd2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06665-5https://doaj.org/toc/2041-1723PWWP2A is a chromatin-binding transcriptional regulator that mediates mitosis-progression. Here, the authors provide evidence that PWWP2A directly interacts with H2A.Z nucleosomes, DNA and H3K36me3, binds to an MTA1-specific subcomplex of the NuRD complex (M1HR) and promotes changes to histone acetylation.Stephanie LinkRamona M. M. SpitzerMaryam SanaMario TorradoMoritz C. Völker-AlbertEva C. KeilhauerThomas BurgoldSebastian PünzelerJason K. K. LowIda LindströmAndrea NistCatherine RegnardThorsten StieweBrian HendrichAxel ImhofMatthias MannJoel P. MackayMarek BartkuhnSandra B. HakeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Stephanie Link Ramona M. M. Spitzer Maryam Sana Mario Torrado Moritz C. Völker-Albert Eva C. Keilhauer Thomas Burgold Sebastian Pünzeler Jason K. K. Low Ida Lindström Andrea Nist Catherine Regnard Thorsten Stiewe Brian Hendrich Axel Imhof Matthias Mann Joel P. Mackay Marek Bartkuhn Sandra B. Hake PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex |
| description |
PWWP2A is a chromatin-binding transcriptional regulator that mediates mitosis-progression. Here, the authors provide evidence that PWWP2A directly interacts with H2A.Z nucleosomes, DNA and H3K36me3, binds to an MTA1-specific subcomplex of the NuRD complex (M1HR) and promotes changes to histone acetylation. |
| format |
article |
| author |
Stephanie Link Ramona M. M. Spitzer Maryam Sana Mario Torrado Moritz C. Völker-Albert Eva C. Keilhauer Thomas Burgold Sebastian Pünzeler Jason K. K. Low Ida Lindström Andrea Nist Catherine Regnard Thorsten Stiewe Brian Hendrich Axel Imhof Matthias Mann Joel P. Mackay Marek Bartkuhn Sandra B. Hake |
| author_facet |
Stephanie Link Ramona M. M. Spitzer Maryam Sana Mario Torrado Moritz C. Völker-Albert Eva C. Keilhauer Thomas Burgold Sebastian Pünzeler Jason K. K. Low Ida Lindström Andrea Nist Catherine Regnard Thorsten Stiewe Brian Hendrich Axel Imhof Matthias Mann Joel P. Mackay Marek Bartkuhn Sandra B. Hake |
| author_sort |
Stephanie Link |
| title |
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex |
| title_short |
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex |
| title_full |
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex |
| title_fullStr |
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex |
| title_full_unstemmed |
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex |
| title_sort |
pwwp2a binds distinct chromatin moieties and interacts with an mta1-specific core nurd complex |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/014b47e5311d4e1aa8fa73d95eb91cdd |
| work_keys_str_mv |
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