Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Abstract The association between physical activity and risk of abdominal aortic aneurysm has been inconsistent with some studies reporting a reduced risk while others have found no association. We conducted a systematic review and meta-analysis of prospective studies to quantify the association. Pub...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Dagfinn Aune, Abhijit Sen, Elsa Kobeissi, Mark Hamer, Teresa Norat, Elio Riboli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0159ea28602f48af88c5a7dc6877775e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0159ea28602f48af88c5a7dc6877775e
record_format	dspace
spelling	oai:doaj.org-article:0159ea28602f48af88c5a7dc6877775e2021-12-02T13:34:00ZPhysical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies10.1038/s41598-020-76306-92045-2322https://doaj.org/article/0159ea28602f48af88c5a7dc6877775e2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-76306-9https://doaj.org/toc/2045-2322Abstract The association between physical activity and risk of abdominal aortic aneurysm has been inconsistent with some studies reporting a reduced risk while others have found no association. We conducted a systematic review and meta-analysis of prospective studies to quantify the association. PubMed and Embase databases were searched up to 3 October 2020. Prospective studies were included if they reported adjusted relative risk (RR) estimates and 95% confidence intervals (CIs) of abdominal aortic aneurysm associated with physical activity. Summary RRs (95% CIs) were estimated using a random effects model. Nine prospective studies (2073 cases, 409,732 participants) were included. The summary RR for high vs. low physical activity was 0.70 (95% CI: 0.56–0.87, I2 = 58%) and per 20 metabolic equivalent task (MET)-hours/week increase of activity was 0.84 (95% CI: 0.74–0.95, I2 = 59%, n = 6). Although the test for nonlinearity was not significant (p = 0.09) the association appeared to be stronger when increasing the physical activity level from 0 to around 20–25 MET-hours/week than at higher levels. The current meta-analysis suggest that higher physical activity may reduce the risk of abdominal aortic aneurysm, however, further studies are needed to clarify the dose–response relationship between different subtypes and intensities of activity and abdominal aortic aneurysm risk.Dagfinn AuneAbhijit SenElsa KobeissiMark HamerTeresa NoratElio RiboliNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dagfinn Aune Abhijit Sen Elsa Kobeissi Mark Hamer Teresa Norat Elio Riboli Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
description	Abstract The association between physical activity and risk of abdominal aortic aneurysm has been inconsistent with some studies reporting a reduced risk while others have found no association. We conducted a systematic review and meta-analysis of prospective studies to quantify the association. PubMed and Embase databases were searched up to 3 October 2020. Prospective studies were included if they reported adjusted relative risk (RR) estimates and 95% confidence intervals (CIs) of abdominal aortic aneurysm associated with physical activity. Summary RRs (95% CIs) were estimated using a random effects model. Nine prospective studies (2073 cases, 409,732 participants) were included. The summary RR for high vs. low physical activity was 0.70 (95% CI: 0.56–0.87, I2 = 58%) and per 20 metabolic equivalent task (MET)-hours/week increase of activity was 0.84 (95% CI: 0.74–0.95, I2 = 59%, n = 6). Although the test for nonlinearity was not significant (p = 0.09) the association appeared to be stronger when increasing the physical activity level from 0 to around 20–25 MET-hours/week than at higher levels. The current meta-analysis suggest that higher physical activity may reduce the risk of abdominal aortic aneurysm, however, further studies are needed to clarify the dose–response relationship between different subtypes and intensities of activity and abdominal aortic aneurysm risk.
format	article
author	Dagfinn Aune Abhijit Sen Elsa Kobeissi Mark Hamer Teresa Norat Elio Riboli
author_facet	Dagfinn Aune Abhijit Sen Elsa Kobeissi Mark Hamer Teresa Norat Elio Riboli
author_sort	Dagfinn Aune
title	Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
title_short	Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
title_full	Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
title_fullStr	Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
title_full_unstemmed	Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
title_sort	physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0159ea28602f48af88c5a7dc6877775e
work_keys_str_mv	AT dagfinnaune physicalactivityandtheriskofabdominalaorticaneurysmasystematicreviewandmetaanalysisofprospectivestudies AT abhijitsen physicalactivityandtheriskofabdominalaorticaneurysmasystematicreviewandmetaanalysisofprospectivestudies AT elsakobeissi physicalactivityandtheriskofabdominalaorticaneurysmasystematicreviewandmetaanalysisofprospectivestudies AT markhamer physicalactivityandtheriskofabdominalaorticaneurysmasystematicreviewandmetaanalysisofprospectivestudies AT teresanorat physicalactivityandtheriskofabdominalaorticaneurysmasystematicreviewandmetaanalysisofprospectivestudies AT elioriboli physicalactivityandtheriskofabdominalaorticaneurysmasystematicreviewandmetaanalysisofprospectivestudies
_version_	1718392774424788992

Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Ejemplares similares