A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT

Abstract Lack of conal rotation and conal malseptation is a characteristic anatomical feature for TOF which lead to dextroposed position of aorta and significant RVOT narrowing. The quantitative assessment of these anatomical features using modern cardiac imaging modality has been rarely discussed i...

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Autores principales:	Soha Romeih, Alaa Kaoud, Mohamed Hashem, Mohamed Abdelfattah, Mohamed Gibreel, Mohamed Elzoghby, Mahmoud Shaaban, Wesam El Mozy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/015e86ae74e049cb96a3d0adbbbb9a4d
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spelling	oai:doaj.org-article:015e86ae74e049cb96a3d0adbbbb9a4d2021-12-02T15:33:00ZA quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT10.1038/s41598-021-93814-42045-2322https://doaj.org/article/015e86ae74e049cb96a3d0adbbbb9a4d2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93814-4https://doaj.org/toc/2045-2322Abstract Lack of conal rotation and conal malseptation is a characteristic anatomical feature for TOF which lead to dextroposed position of aorta and significant RVOT narrowing. The quantitative assessment of these anatomical features using modern cardiac imaging modality has been rarely discussed in the literature. All TOF scanned had in our center from 2013 till 2019 were included. The angle of aortic root rotation was recorded by measuring the angle between a line connecting the midpoint of the non-coronary sinus to the anterior commissure and another line along the interatrial septum. Rotation angles were correlated with proximal main pulmonary artery (MPA) size indexed to BSA. 287 TOF patients were included, 258 patients (91%) had TOF with pulmonary stenosis (TOF-PS) including 138 male (54%), median age 2 years (2 months–40 years), and 29 patients (9%) had TOF with pulmonary atresia (TOF-PA) including 17 male (59%), median age 5 years (1 m-33 years). The whole cases demonstrated clockwise rotation of the aortic root. The mean rotation angle in TOF-PS group was 52.6 ± 20.9° and in TOF-PA group was 64.9 ± 13.9°. Proximal MPA diameter was 11.1 ± 5.9 mm/m2. There was a significant negative correlation between aortic root rotation angle and proximal MPA diameter (r = − 0.262, P = 0.000). The rotation angle of aortic root was significantly higher in TOF-PA compared to TOF-PS (64.9 ± 13.9° vs. 52.6 ± 20.9°, P = 0.001, respectively). MSCT provide a quantitative measurement methodology of conal malseptation and its effect in TOF patients. There is a clockwise rotation angle of the aortic root in TOF patients that correlates negatively with proximal MPA size. TOF-PA have a larger rotation angle of aortic root.Soha RomeihAlaa KaoudMohamed HashemMohamed AbdelfattahMohamed GibreelMohamed ElzoghbyMahmoud ShaabanWesam El MozyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Soha Romeih Alaa Kaoud Mohamed Hashem Mohamed Abdelfattah Mohamed Gibreel Mohamed Elzoghby Mahmoud Shaaban Wesam El Mozy A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT
description	Abstract Lack of conal rotation and conal malseptation is a characteristic anatomical feature for TOF which lead to dextroposed position of aorta and significant RVOT narrowing. The quantitative assessment of these anatomical features using modern cardiac imaging modality has been rarely discussed in the literature. All TOF scanned had in our center from 2013 till 2019 were included. The angle of aortic root rotation was recorded by measuring the angle between a line connecting the midpoint of the non-coronary sinus to the anterior commissure and another line along the interatrial septum. Rotation angles were correlated with proximal main pulmonary artery (MPA) size indexed to BSA. 287 TOF patients were included, 258 patients (91%) had TOF with pulmonary stenosis (TOF-PS) including 138 male (54%), median age 2 years (2 months–40 years), and 29 patients (9%) had TOF with pulmonary atresia (TOF-PA) including 17 male (59%), median age 5 years (1 m-33 years). The whole cases demonstrated clockwise rotation of the aortic root. The mean rotation angle in TOF-PS group was 52.6 ± 20.9° and in TOF-PA group was 64.9 ± 13.9°. Proximal MPA diameter was 11.1 ± 5.9 mm/m2. There was a significant negative correlation between aortic root rotation angle and proximal MPA diameter (r = − 0.262, P = 0.000). The rotation angle of aortic root was significantly higher in TOF-PA compared to TOF-PS (64.9 ± 13.9° vs. 52.6 ± 20.9°, P = 0.001, respectively). MSCT provide a quantitative measurement methodology of conal malseptation and its effect in TOF patients. There is a clockwise rotation angle of the aortic root in TOF patients that correlates negatively with proximal MPA size. TOF-PA have a larger rotation angle of aortic root.
format	article
author	Soha Romeih Alaa Kaoud Mohamed Hashem Mohamed Abdelfattah Mohamed Gibreel Mohamed Elzoghby Mahmoud Shaaban Wesam El Mozy
author_facet	Soha Romeih Alaa Kaoud Mohamed Hashem Mohamed Abdelfattah Mohamed Gibreel Mohamed Elzoghby Mahmoud Shaaban Wesam El Mozy
author_sort	Soha Romeih
title	A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT
title_short	A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT
title_full	A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT
title_fullStr	A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT
title_full_unstemmed	A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT
title_sort	quantitative assessment of aorta root rotation in patients with tetralogy of fallot evaluated by msct
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/015e86ae74e049cb96a3d0adbbbb9a4d
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A quantitative assessment of aorta root rotation in patients with tetralogy of Fallot evaluated by MSCT

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