Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice

Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice

Schizophrenia is associated with brain ventricular enlargement. Here, the authors show in mice that 22q11 deletion, which is associated with schizophrenia, causes ventricular enlargement and motility abnormalities in cilia lining ventricle walls via a microRNA mechanism.

Guardado en:
Detalles Bibliográficos
Autores principales: Tae-Yeon Eom, Seung Baek Han, Jieun Kim, Jay A. Blundon, Yong-Dong Wang, Jing Yu, Kara Anderson, Damian B. Kaminski, Sadie Miki Sakurada, Shondra M. Pruett-Miller, Linda Horner, Ben Wagner, Camenzind G. Robinson, Matthew Eicholtz, Derek C. Rose, Stanislav S. Zakharenko
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/015f5351a7344fa99035595c0123d9f5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Schizophrenia is associated with brain ventricular enlargement. Here, the authors show in mice that 22q11 deletion, which is associated with schizophrenia, causes ventricular enlargement and motility abnormalities in cilia lining ventricle walls via a microRNA mechanism.

Ejemplares similares