A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila cells to identify proteins required for centriole duplication and mitotic PCM recruitment. We analys...

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Bibliographic Details
Main Authors: Jeroen Dobbelaere, Filipe Josué, Saskia Suijkerbuijk, Buzz Baum, Nicolas Tapon, Jordan Raff
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
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Online Access:https://doaj.org/article/0164a7f2fa144f4e9a1595fc7254c021
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