ROCK regulates the intermittent mode of interstitial T cell migration in inflamed lungs

ROCK is associated with T cell movement in lymph nodes. Here the authors use an LPS lung damage model and two-photon imaging to show that CD8+ T cells in lung tissue engage in ROCK-dependent fast linear migration alternating with bursts of slower confined migration that together optimize contact wit...

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Auteurs principaux: Paulus Mrass, Sreenivasa Rao Oruganti, G. Matthew Fricke, Justyna Tafoya, Janie R. Byrum, Lihua Yang, Samantha L. Hamilton, Mark J. Miller, Melanie E. Moses, Judy L. Cannon
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/0164cac4b97b4f608d1a66e156f4b2bd
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