Histopathological study of canine hepatoid gland tumours

Hepatoid gland neoplasms arise due to disorganized and uncontrolled proliferation of cells of hepatoid glands. These are the modified sebaceous glands located mainly in the perianal area. Gross and histological findings of canine hepatoid gland tumours were evaluated. Dogs of different breed, age an...

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Autores principales: P.M. Shabeeba, I.S. Sajitha, S. S. Devi, C. Divya, Sudheesh S. Nair
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Publicado: Director of Academics and Research, Kerala Veterinary and Animal Sciences University 2021
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spelling oai:doaj.org-article:016cbb1bc6ea4e08a42c953b00e809702021-11-18T13:31:16ZHistopathological study of canine hepatoid gland tumours 10.51966/jvas.2021.52.3.277-2800971-07012582-0605https://doaj.org/article/016cbb1bc6ea4e08a42c953b00e809702021-07-01T00:00:00Zhttps://www.jvas.in/public_html/upload/article_file/article_file_r0qm5b.pdf?t=r0qm5bhttps://doaj.org/toc/0971-0701https://doaj.org/toc/2582-0605Hepatoid gland neoplasms arise due to disorganized and uncontrolled proliferation of cells of hepatoid glands. These are the modified sebaceous glands located mainly in the perianal area. Gross and histological findings of canine hepatoid gland tumours were evaluated. Dogs of different breed, age and sex that were presented to Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy formed the materials for the present study. Grossly, tumours were solitary or multiple irregular shaped intradermal masses. The excisional biopsy samples were collected in 10 per cent neutral buffered formalin after surgical removal of tumour mass. Histopathologically, the masses were encircled by fibrovascular capsule which extended to the parenchyma as tumour stroma, which separated it into lobules. Two cases of hepatoid gland adenoma one case of hepatoid gland epithelioma and two cases of carcinoma were recognised on histopathological examination. Hepatoid adenoma were characterised by proliferation of hepatocyte like hepatoid gland epithelial cells with extensive sebaceous differentiation and were arranged in cords and anastomosing trabeculae. In hepatoid gland epithelioma, many of the cells were basaloid reserve cells with fewer hepatocyte like cells. Histopathological examination of carcinoma revealed irregular arrangement of the hepatoid cells which showed varying degrees of maturation and marked nuclear pleomorphism. The malignant hepatoid cells had abundant eosinophilic cytoplasm and large nuclei with several prominent nucleoli and mitotic figures. P.M. ShabeebaI.S. SajithaS. S. DeviC. DivyaSudheesh S. NairDirector of Academics and Research, Kerala Veterinary and Animal Sciences Universityarticlecaninehepatoid gland adenomahepatoid gland epitheliomahepatoid gland carcinomaAnimal biochemistryQP501-801Science (General)Q1-390ENJournal of Veterinary and Animal Sciences, Vol 52, Iss 3, Pp 277-280 (2021)
institution DOAJ
collection DOAJ
language EN
topic canine
hepatoid gland adenoma
hepatoid gland epithelioma
hepatoid gland carcinoma
Animal biochemistry
QP501-801
Science (General)
Q1-390
spellingShingle canine
hepatoid gland adenoma
hepatoid gland epithelioma
hepatoid gland carcinoma
Animal biochemistry
QP501-801
Science (General)
Q1-390
P.M. Shabeeba
I.S. Sajitha
S. S. Devi
C. Divya
Sudheesh S. Nair
Histopathological study of canine hepatoid gland tumours
description Hepatoid gland neoplasms arise due to disorganized and uncontrolled proliferation of cells of hepatoid glands. These are the modified sebaceous glands located mainly in the perianal area. Gross and histological findings of canine hepatoid gland tumours were evaluated. Dogs of different breed, age and sex that were presented to Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy formed the materials for the present study. Grossly, tumours were solitary or multiple irregular shaped intradermal masses. The excisional biopsy samples were collected in 10 per cent neutral buffered formalin after surgical removal of tumour mass. Histopathologically, the masses were encircled by fibrovascular capsule which extended to the parenchyma as tumour stroma, which separated it into lobules. Two cases of hepatoid gland adenoma one case of hepatoid gland epithelioma and two cases of carcinoma were recognised on histopathological examination. Hepatoid adenoma were characterised by proliferation of hepatocyte like hepatoid gland epithelial cells with extensive sebaceous differentiation and were arranged in cords and anastomosing trabeculae. In hepatoid gland epithelioma, many of the cells were basaloid reserve cells with fewer hepatocyte like cells. Histopathological examination of carcinoma revealed irregular arrangement of the hepatoid cells which showed varying degrees of maturation and marked nuclear pleomorphism. The malignant hepatoid cells had abundant eosinophilic cytoplasm and large nuclei with several prominent nucleoli and mitotic figures.
format article
author P.M. Shabeeba
I.S. Sajitha
S. S. Devi
C. Divya
Sudheesh S. Nair
author_facet P.M. Shabeeba
I.S. Sajitha
S. S. Devi
C. Divya
Sudheesh S. Nair
author_sort P.M. Shabeeba
title Histopathological study of canine hepatoid gland tumours
title_short Histopathological study of canine hepatoid gland tumours
title_full Histopathological study of canine hepatoid gland tumours
title_fullStr Histopathological study of canine hepatoid gland tumours
title_full_unstemmed Histopathological study of canine hepatoid gland tumours
title_sort histopathological study of canine hepatoid gland tumours
publisher Director of Academics and Research, Kerala Veterinary and Animal Sciences University
publishDate 2021
url https://doaj.org/article/016cbb1bc6ea4e08a42c953b00e80970
work_keys_str_mv AT pmshabeeba histopathologicalstudyofcaninehepatoidglandtumours
AT issajitha histopathologicalstudyofcaninehepatoidglandtumours
AT ssdevi histopathologicalstudyofcaninehepatoidglandtumours
AT cdivya histopathologicalstudyofcaninehepatoidglandtumours
AT sudheeshsnair histopathologicalstudyofcaninehepatoidglandtumours
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