Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment

Eglailson Dantas Almeida J&uacute;nior1, Luciano Moreira Pinto1,2, Rodrigo Antonio Brant Fernandes1,2, Tiago Santos Prata1,31Department of Ophthalmology, Federal University of S&atilde;o Paulo, S&atilde;o Paulo, Brazil; 2Cerpo Oftalmologia, S&atilde;o Paulo, Brazil; 3...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Almeida Jr ED, Pinto LM, Fernandes RB, Prata TS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/01789262385d4744bd69426eb83a993b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:01789262385d4744bd69426eb83a993b
record_format	dspace
spelling	oai:doaj.org-article:01789262385d4744bd69426eb83a993b2021-12-02T00:32:40ZPattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment1177-54671177-5483https://doaj.org/article/01789262385d4744bd69426eb83a993b2011-07-01T00:00:00Zhttp://www.dovepress.com/pattern-of-intraocular-pressure-reduction-following-laser-trabeculopla-a7826https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Eglailson Dantas Almeida J&uacute;nior1, Luciano Moreira Pinto1,2, Rodrigo Antonio Brant Fernandes1,2, Tiago Santos Prata1,31Department of Ophthalmology, Federal University of S&atilde;o Paulo, S&atilde;o Paulo, Brazil; 2Cerpo Oftalmologia, S&atilde;o Paulo, Brazil; 3Hospital Medicina dos Olhos, S&atilde;o Paulo, BrazilObjective: To compare the pattern of intraocular pressure (IOP) reduction following selective laser trabeculoplasty (SLT) versus argon laser trabeculoplasty (ALT) in open-angle glaucoma (OAG) patients, and to investigate the ability of initial IOP reduction to predict mid-term success.Methods: A prospective, nonrandomized, interventional case series was carried out. Consecutive uncontrolled OAG glaucoma patients underwent SLT or ALT; the same preoperative medical regimen was maintained during follow-up. Data collected included age, type of OAG, pre- and postoperative IOP, number of glaucoma medications, and surgical complications. Post-treatment assessments were scheduled at day 1 and 7 and months 1, 3, and 6.Results: A total of 45 patients (45 eyes) were enrolled [SLT group (n = 25); ALT group (n = 20)]. Groups were similar for age, baseline IOP, and number of glaucoma medications (P &ge; 0.12). We found no significant differences in mean IOP reduction between SLT (5.1 &plusmn; 2.5 mmHg; 26.6%) and ALT (4.4 &plusmn; 2.8 mmHg; 22.8%) groups at month 6 (P = 0.38). Success rates (IOP &le; 16 mmHg and IOP reduction &ge;25%) at last follow-up visit were similar for SLT (72%) and ALT (65%) groups (P = 0.36). Comparing the pattern of IOP reduction (% of IOP reduction at each visit) between groups, we found a greater effect following SLT compared with ALT at day 7 (23.7% &plusmn; 13.7% vs 8.1% &plusmn; 9.5%; P &lt; 0.001). No significant differences were observed at other time points (P &ge; 0.32). Additionally, the percentage of IOP reduction at day 7 and at month 6 were significantly correlated in the SLT group (R2 = 0.36; P &lt; 0.01), but not in the ALT group (P = 0.89). Early postoperative success predicted late success in most SLT cases (82%). No serious complications were observed.Conclusion: Although mid-term results suggest SLT and ALT as effective and equivalent alternatives, a greater initial IOP reduction was observed following SLT. In addition, the initial IOP reduction was a good predictor of mid-term success in patients undergoing SLT, but not ALT.Keywords: open-angle glaucoma, laser trabeculoplasty, intraocular pressureAlmeida Jr EDPinto LMFernandes RBPrata TSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 933-936 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Almeida Jr ED Pinto LM Fernandes RB Prata TS Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
description	Eglailson Dantas Almeida J&uacute;nior1, Luciano Moreira Pinto1,2, Rodrigo Antonio Brant Fernandes1,2, Tiago Santos Prata1,31Department of Ophthalmology, Federal University of S&atilde;o Paulo, S&atilde;o Paulo, Brazil; 2Cerpo Oftalmologia, S&atilde;o Paulo, Brazil; 3Hospital Medicina dos Olhos, S&atilde;o Paulo, BrazilObjective: To compare the pattern of intraocular pressure (IOP) reduction following selective laser trabeculoplasty (SLT) versus argon laser trabeculoplasty (ALT) in open-angle glaucoma (OAG) patients, and to investigate the ability of initial IOP reduction to predict mid-term success.Methods: A prospective, nonrandomized, interventional case series was carried out. Consecutive uncontrolled OAG glaucoma patients underwent SLT or ALT; the same preoperative medical regimen was maintained during follow-up. Data collected included age, type of OAG, pre- and postoperative IOP, number of glaucoma medications, and surgical complications. Post-treatment assessments were scheduled at day 1 and 7 and months 1, 3, and 6.Results: A total of 45 patients (45 eyes) were enrolled [SLT group (n = 25); ALT group (n = 20)]. Groups were similar for age, baseline IOP, and number of glaucoma medications (P &ge; 0.12). We found no significant differences in mean IOP reduction between SLT (5.1 &plusmn; 2.5 mmHg; 26.6%) and ALT (4.4 &plusmn; 2.8 mmHg; 22.8%) groups at month 6 (P = 0.38). Success rates (IOP &le; 16 mmHg and IOP reduction &ge;25%) at last follow-up visit were similar for SLT (72%) and ALT (65%) groups (P = 0.36). Comparing the pattern of IOP reduction (% of IOP reduction at each visit) between groups, we found a greater effect following SLT compared with ALT at day 7 (23.7% &plusmn; 13.7% vs 8.1% &plusmn; 9.5%; P &lt; 0.001). No significant differences were observed at other time points (P &ge; 0.32). Additionally, the percentage of IOP reduction at day 7 and at month 6 were significantly correlated in the SLT group (R2 = 0.36; P &lt; 0.01), but not in the ALT group (P = 0.89). Early postoperative success predicted late success in most SLT cases (82%). No serious complications were observed.Conclusion: Although mid-term results suggest SLT and ALT as effective and equivalent alternatives, a greater initial IOP reduction was observed following SLT. In addition, the initial IOP reduction was a good predictor of mid-term success in patients undergoing SLT, but not ALT.Keywords: open-angle glaucoma, laser trabeculoplasty, intraocular pressure
format	article
author	Almeida Jr ED Pinto LM Fernandes RB Prata TS
author_facet	Almeida Jr ED Pinto LM Fernandes RB Prata TS
author_sort	Almeida Jr ED
title	Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
title_short	Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
title_full	Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
title_fullStr	Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
title_full_unstemmed	Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
title_sort	pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/01789262385d4744bd69426eb83a993b
work_keys_str_mv	AT almeidajred patternofintraocularpressurereductionfollowinglasertrabeculoplastyinopenangleglaucomapatientscomparisonbetweenselectiveandnonselectivetreatment AT pintolm patternofintraocularpressurereductionfollowinglasertrabeculoplastyinopenangleglaucomapatientscomparisonbetweenselectiveandnonselectivetreatment AT fernandesrb patternofintraocularpressurereductionfollowinglasertrabeculoplastyinopenangleglaucomapatientscomparisonbetweenselectiveandnonselectivetreatment AT pratats patternofintraocularpressurereductionfollowinglasertrabeculoplastyinopenangleglaucomapatientscomparisonbetweenselectiveandnonselectivetreatment
_version_	1718403655893254144

Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment

Ejemplares similares