Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

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Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

The COVID-19 pandemic has highlighted the need for user-friendly diagnostic techniques. Here, the authors present SHINE, a streamlined and optimised Cas13-based method with accompanying smartphone app for visual diagnosis.

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Bibliographic Details
Main Authors:	Jon Arizti-Sanz, Catherine A. Freije, Alexandra C. Stanton, Brittany A. Petros, Chloe K. Boehm, Sameed Siddiqui, Bennett M. Shaw, Gordon Adams, Tinna-Solveig F. Kosoko-Thoroddsen, Molly E. Kemball, Jessica N. Uwanibe, Fehintola V. Ajogbasile, Philomena E. Eromon, Robin Gross, Loni Wronka, Katie Caviness, Lisa E. Hensley, Nicholas H. Bergman, Bronwyn L. MacInnis, Christian T. Happi, Jacob E. Lemieux, Pardis C. Sabeti, Cameron Myhrvold
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/018fb940dfad4d76bcf2272a15c0148b
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Description
Summary:	The COVID-19 pandemic has highlighted the need for user-friendly diagnostic techniques. Here, the authors present SHINE, a streamlined and optimised Cas13-based method with accompanying smartphone app for visual diagnosis.