High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale

Current 3C methods generate low-resolution interaction profiles across the genome or high-resolution profiles at a limited number of loci. Here the authors present Nuclear-Titrated Capture-C which produces high-resolution genome-wide interaction profiles.

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Autores principales:	Damien J. Downes, Robert A. Beagrie, Matthew E. Gosden, Jelena Telenius, Stephanie J. Carpenter, Lea Nussbaum, Sara De Ornellas, Martin Sergeant, Chris Q. Eijsbouts, Ron Schwessinger, Jon Kerry, Nigel Roberts, Arun Shivalingam, Afaf El-Sagheer, A. Marieke Oudelaar, Tom Brown, Veronica J. Buckle, James O. J. Davies, Jim R. Hughes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0197837fb40c491eb660e62c1a29c968
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spelling	oai:doaj.org-article:0197837fb40c491eb660e62c1a29c9682021-12-02T13:51:03ZHigh-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale10.1038/s41467-020-20809-62041-1723https://doaj.org/article/0197837fb40c491eb660e62c1a29c9682021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20809-6https://doaj.org/toc/2041-1723Current 3C methods generate low-resolution interaction profiles across the genome or high-resolution profiles at a limited number of loci. Here the authors present Nuclear-Titrated Capture-C which produces high-resolution genome-wide interaction profiles.Damien J. DownesRobert A. BeagrieMatthew E. GosdenJelena TeleniusStephanie J. CarpenterLea NussbaumSara De OrnellasMartin SergeantChris Q. EijsboutsRon SchwessingerJon KerryNigel RobertsArun ShivalingamAfaf El-SagheerA. Marieke OudelaarTom BrownVeronica J. BuckleJames O. J. DaviesJim R. HughesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Damien J. Downes Robert A. Beagrie Matthew E. Gosden Jelena Telenius Stephanie J. Carpenter Lea Nussbaum Sara De Ornellas Martin Sergeant Chris Q. Eijsbouts Ron Schwessinger Jon Kerry Nigel Roberts Arun Shivalingam Afaf El-Sagheer A. Marieke Oudelaar Tom Brown Veronica J. Buckle James O. J. Davies Jim R. Hughes High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
description	Current 3C methods generate low-resolution interaction profiles across the genome or high-resolution profiles at a limited number of loci. Here the authors present Nuclear-Titrated Capture-C which produces high-resolution genome-wide interaction profiles.
format	article
author	Damien J. Downes Robert A. Beagrie Matthew E. Gosden Jelena Telenius Stephanie J. Carpenter Lea Nussbaum Sara De Ornellas Martin Sergeant Chris Q. Eijsbouts Ron Schwessinger Jon Kerry Nigel Roberts Arun Shivalingam Afaf El-Sagheer A. Marieke Oudelaar Tom Brown Veronica J. Buckle James O. J. Davies Jim R. Hughes
author_facet	Damien J. Downes Robert A. Beagrie Matthew E. Gosden Jelena Telenius Stephanie J. Carpenter Lea Nussbaum Sara De Ornellas Martin Sergeant Chris Q. Eijsbouts Ron Schwessinger Jon Kerry Nigel Roberts Arun Shivalingam Afaf El-Sagheer A. Marieke Oudelaar Tom Brown Veronica J. Buckle James O. J. Davies Jim R. Hughes
author_sort	Damien J. Downes
title	High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
title_short	High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
title_full	High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
title_fullStr	High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
title_full_unstemmed	High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
title_sort	high-resolution targeted 3c interrogation of cis-regulatory element organization at genome-wide scale
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0197837fb40c491eb660e62c1a29c968
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High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale

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