Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila

Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila

The role of the nuclear lamina (NL) in chromatin architecture is still poorly understood. Here, the authors provide evidence that disruption of the NL in Drosophila cells leads to overall chromatin compaction and repositioning from the nuclear envelope, whereas lamina-associated regions become less...

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Autores principales: Sergey V. Ulianov, Semen A. Doronin, Ekaterina E. Khrameeva, Pavel I. Kos, Artem V. Luzhin, Sergei S. Starikov, Aleksandra A. Galitsyna, Valentina V. Nenasheva, Artem A. Ilyin, Ilya M. Flyamer, Elena A. Mikhaleva, Mariya D. Logacheva, Mikhail S. Gelfand, Alexander V. Chertovich, Alexey A. Gavrilov, Sergey V. Razin, Yuri Y. Shevelyov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/019c5aaf61ed41efb63d52b8af38836b
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