Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice

Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice

Abstract In a previous transcriptomic study of human bone marrow stromal cells (BMSCs, also known as bone marrow-derived “mesenchymal stem cells”), SFRP2 was highly over-represented in a subset of multipotent BMSCs (skeletal stem cells, SSCs), which recreate a bone/marrow organ in an in vivo ectopic...

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Detalles Bibliográficos
Autores principales: Luis Fernandez de Castro, Brian J. Sworder, Byron Mui, Kathryn Futrega, Agnes Berendsen, Matthew D. Phillips, Nathan J. Burbach, Natasha Cherman, Sergei Kuznetsov, Yankel Gabet, Kenn Holmbeck, Pamela G. Robey
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Biology (General)
QH301-705.5
Physiology
QP1-981
Acceso en línea:https://doaj.org/article/01a82cd57e0d47c091b9d82673e78dcd
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