MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization.

MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization.

Human infections with highly pathogenic avian influenza viruses of the H5N1 subtype, frequently reported since 2003, result in high morbidity and mortality. It is feared that these viruses become pandemic, therefore the development of safe and effective vaccines is desirable. MVA-based H5N1 vaccines...

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Main Authors: Joost H C M Kreijtz, Yasemin Suezer, Gerrie de Mutsert, Geert van Amerongen, Astrid Schwantes, Judith M A van den Brand, Ron A M Fouchier, Johannes Löwer, Albert D M E Osterhaus, Gerd Sutter, Guus F Rimmelzwaan
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/01ad0564450c46c4b13c74add8a2d0af
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