Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls
BACKGROUND AND OBJECTIVE: The role of polyunsaturated fatty acids (PUFA) especially omega-3 has been explored in many diseases. However, the profile of PUFA in depressed patients is not established. The aim of this study was to measure the amount of DHA (Docosahexaenoic acid) and EPA (Eicosapentaeno...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN FA |
| Publicado: |
Babol University of Medical Sciences
2010
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/01b018fc6bff4a0f804db77891cfa100 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:01b018fc6bff4a0f804db77891cfa100 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:01b018fc6bff4a0f804db77891cfa1002021-11-10T09:00:30ZComparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls1561-41072251-7170https://doaj.org/article/01b018fc6bff4a0f804db77891cfa1002010-08-01T00:00:00Zhttp://jbums.org/article-1-3631-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: The role of polyunsaturated fatty acids (PUFA) especially omega-3 has been explored in many diseases. However, the profile of PUFA in depressed patients is not established. The aim of this study was to measure the amount of DHA (Docosahexaenoic acid) and EPA (Eicosapentaenoic acid) in depressed and suicide group, compared to control group. METHODS: In a case–control study the amount of DHA and EPA in blood of 27 depressed patients, 32 attempted to suicide patients and 35 normal people were measured by gas-chromatography and then compared.FINDINGS: The amount of DHA in depressed and attempted to suicide patients and control group was 2.48±0.22, 2.25±0.24 and, 4.6±0.13 mg/ml, respectively (p<0.001). However, there was not significant difference between depressed and attempted to suicide patients in this regard. The amount of EPA in attempted to suicide patients (0.44±0.05 mg/ml) was less in comparison to depressed (0.84±0.20 mg/ml) or control (0.95±0.11 mg/ml) groups (p<0.001).CONCLUSION: It seems that there is a relation between the amount of DHA or EPA and attempt to suicide in depressed patients. However, in less severe depressed patients just DHA is changed, not EPA.MR Khanmohammadi,F AbdiR Haji Hoseini,M RafieianBabol University of Medical Sciencesarticledepressive patientssuicideunsaturated fatty acidsgas-chromatographyMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 12, Iss 3, Pp 43-49 (2010) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN FA |
| topic |
depressive patients suicide unsaturated fatty acids gas-chromatography Medicine R Medicine (General) R5-920 |
| spellingShingle |
depressive patients suicide unsaturated fatty acids gas-chromatography Medicine R Medicine (General) R5-920 MR Khanmohammadi, F Abdi R Haji Hoseini, M Rafieian Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls |
| description |
BACKGROUND AND OBJECTIVE: The role of polyunsaturated fatty acids (PUFA) especially omega-3 has been explored in many diseases. However, the profile of PUFA in depressed patients is not established. The aim of this study was to measure the amount of DHA (Docosahexaenoic acid) and EPA (Eicosapentaenoic acid) in depressed and suicide group, compared to control group. METHODS: In a case–control study the amount of DHA and EPA in blood of 27 depressed patients, 32 attempted to suicide patients and 35 normal people were measured by gas-chromatography and then compared.FINDINGS: The amount of DHA in depressed and attempted to suicide patients and control group was 2.48±0.22, 2.25±0.24 and, 4.6±0.13 mg/ml, respectively (p<0.001). However, there was not significant difference between depressed and attempted to suicide patients in this regard. The amount of EPA in attempted to suicide patients (0.44±0.05 mg/ml) was less in comparison to depressed (0.84±0.20 mg/ml) or control (0.95±0.11 mg/ml) groups (p<0.001).CONCLUSION: It seems that there is a relation between the amount of DHA or EPA and attempt to suicide in depressed patients. However, in less severe depressed patients just DHA is changed, not EPA. |
| format |
article |
| author |
MR Khanmohammadi, F Abdi R Haji Hoseini, M Rafieian |
| author_facet |
MR Khanmohammadi, F Abdi R Haji Hoseini, M Rafieian |
| author_sort |
MR Khanmohammadi, |
| title |
Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls |
| title_short |
Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls |
| title_full |
Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls |
| title_fullStr |
Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls |
| title_full_unstemmed |
Comparison of Polyunsaturated Fatty Acids in Depressed Patients Attempted Suicide with Healthy Controls |
| title_sort |
comparison of polyunsaturated fatty acids in depressed patients attempted suicide with healthy controls |
| publisher |
Babol University of Medical Sciences |
| publishDate |
2010 |
| url |
https://doaj.org/article/01b018fc6bff4a0f804db77891cfa100 |
| work_keys_str_mv |
AT mrkhanmohammadi comparisonofpolyunsaturatedfattyacidsindepressedpatientsattemptedsuicidewithhealthycontrols AT fabdi comparisonofpolyunsaturatedfattyacidsindepressedpatientsattemptedsuicidewithhealthycontrols AT rhajihoseini comparisonofpolyunsaturatedfattyacidsindepressedpatientsattemptedsuicidewithhealthycontrols AT mrafieian comparisonofpolyunsaturatedfattyacidsindepressedpatientsattemptedsuicidewithhealthycontrols |
| _version_ |
1718440250722746368 |