TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer
Abstract Targeted sequencing for somatic mutations across the hotspots of 50 cancer-related genes was performed using biopsy specimens to investigate whether clinicopathological factors and genomic alterations correlated with prognosis in locally advanced cervical cancer. Seventy patients diagnosed...
Enregistré dans:
Auteurs principaux: | Ikumi Kuno, Daisuke Takayanagi, Yuka Asami, Naoya Murakami, Maiko Matsuda, Yoko Shimada, Sou Hirose, Mayumi Kobayashi Kato, Masaaki Komatsu, Ryuji Hamamoto, Kae Okuma, Takashi Kohno, Jun Itami, Hiroshi Yoshida, Kouya Shiraishi, Tomoyasu Kato |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/01be47dd8ca541d2a942cb3061a4dbb3 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Distribution of genetic alterations in high-risk early-stage cervical cancer patients treated with postoperative radiation therapy
par: Naoya Murakami, et autres
Publié: (2021) -
Evaluation of Tp-e interval and Tp-e: QT and Tp-e: QTc ratios in patients infected with HIV and using antiretroviral therapy
par: Şükrü Çetin, et autres
Publié: (2021) -
TP53 in Myelodysplastic Syndromes
par: Yan Jiang, et autres
Publié: (2021) -
Induction chemotherapy followed by definitive chemoradiotherapy versus chemoradiotherapy alone in esophageal squamous cell carcinoma: a randomized phase II trial
par: Shiliang Liu, et autres
Publié: (2021) -
The investigation of salvage endoscopic laryngopharyngeal surgery after chemoradiotherapy
par: Yohei Kawasaki, et autres
Publié: (2020)