Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis

Zohair Jamil Gazzaz,1 Rahila Iftikhar,2 Tahir Jameel,1 Mukhtiar Baig,3 Manal Abdulaziz Murad2 1Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi...

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Autores principales:	Gazzaz ZJ, Iftikhar R, Jameel T, Baig M, Murad MA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	dyslipidemia dm ihd cholestrol comorbidities hba1c hypertension Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/01c66236b55d4cf38ea03975ff9e6792
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spelling	oai:doaj.org-article:01c66236b55d4cf38ea03975ff9e67922021-12-02T04:38:22ZAssociation of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis1178-7007https://doaj.org/article/01c66236b55d4cf38ea03975ff9e67922020-03-01T00:00:00Zhttps://www.dovepress.com/association-of-dyslipidemia-and-comorbidities-with-risk-factors-among--peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Zohair Jamil Gazzaz,1 Rahila Iftikhar,2 Tahir Jameel,1 Mukhtiar Baig,3 Manal Abdulaziz Murad2 1Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 3Department of Clinical Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Rahila IftikharDepartment of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah 22431, Saudi ArabiaTel +13467541966Email rahila_iftikhar@hotmail.comPurpose: To find out the association of dyslipidemia and comorbidities with risk factors among type-2 diabetes mellitus (T2DM) patients attending King Abdulaziz University Hospital (KAUH) Jeddah, Saudi Arabia (SA).Patients and Methods: Three hundred and twenty-five T2DM patients were enrolled from the electronic record of the KAUH. The patients’ existing comorbidities and dyslipidemia correlation with demographic, clinical, and available laboratory data were sought. Statistical analysis was performed on SPSS-23.Results: Of the total 325 T2DM patients with a mean age of 60.13± 10.5 years [males 95 (29.23%) and females 230 (70.77%)] were included from the electronic record. Poor glycemic control was observed in 222 (68.31%) subjects (HbA1c > 7%), and 154 (47.39%) subjects had DM for more than ten years. Among our study subjects, 103 (31.69%) were hypertensive (HTN), 112 (34.46%) had ischemic heart disease (IHD), 45 (13.85%) were obese, 8(2.46%) had a stroke and 269 (82.77%) had dyslipidemia. Of the total 269 dyslipidemic patients,168 (62.45%) were on hypolipidemic treatment. On comparison of study variables according to dyslipidemia versus normal lipid levels, the lipid profile, including HDLc, LDLc, TC, and TG, revealed a highly significant difference (p-value < 0.001) whereas many variables were not significantly different. HBA1c, FBG, and RBG were significantly higher in dyslipidemic subjects. Logistic regression analysis of risk factors and comorbidities in our patients revealed that age 60– 69 years and 70– 79 years had a significant association with comorbidities. Similarly, logistic regression analysis of risk factors and dyslipidemia in our patients revealed no statistically significant association.Conclusion: Our results observed that the comorbidities were associated with increasing age and common comorbidities were HTN, IHD, dyslipidemia. Our study has highlighted the current trends in T2DM symptomatology and comorbidities. Efficient management and control by early screening and developing healthy lifestyles in our patients can be very helpful in the prevention of all these highly morbid complications of this preventable disease.Keywords: dyslipidemia, DM, IHD, cholesterol, comorbidities, HbA1c, hypertensionGazzaz ZJIftikhar RJameel TBaig MMurad MADove Medical Pressarticledyslipidemiadmihdcholestrolcomorbiditieshba1chypertensionSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 935-941 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	dyslipidemia dm ihd cholestrol comorbidities hba1c hypertension Specialties of internal medicine RC581-951
spellingShingle	dyslipidemia dm ihd cholestrol comorbidities hba1c hypertension Specialties of internal medicine RC581-951 Gazzaz ZJ Iftikhar R Jameel T Baig M Murad MA Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis
description	Zohair Jamil Gazzaz,1 Rahila Iftikhar,2 Tahir Jameel,1 Mukhtiar Baig,3 Manal Abdulaziz Murad2 1Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 3Department of Clinical Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Rahila IftikharDepartment of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah 22431, Saudi ArabiaTel +13467541966Email rahila_iftikhar@hotmail.comPurpose: To find out the association of dyslipidemia and comorbidities with risk factors among type-2 diabetes mellitus (T2DM) patients attending King Abdulaziz University Hospital (KAUH) Jeddah, Saudi Arabia (SA).Patients and Methods: Three hundred and twenty-five T2DM patients were enrolled from the electronic record of the KAUH. The patients’ existing comorbidities and dyslipidemia correlation with demographic, clinical, and available laboratory data were sought. Statistical analysis was performed on SPSS-23.Results: Of the total 325 T2DM patients with a mean age of 60.13± 10.5 years [males 95 (29.23%) and females 230 (70.77%)] were included from the electronic record. Poor glycemic control was observed in 222 (68.31%) subjects (HbA1c > 7%), and 154 (47.39%) subjects had DM for more than ten years. Among our study subjects, 103 (31.69%) were hypertensive (HTN), 112 (34.46%) had ischemic heart disease (IHD), 45 (13.85%) were obese, 8(2.46%) had a stroke and 269 (82.77%) had dyslipidemia. Of the total 269 dyslipidemic patients,168 (62.45%) were on hypolipidemic treatment. On comparison of study variables according to dyslipidemia versus normal lipid levels, the lipid profile, including HDLc, LDLc, TC, and TG, revealed a highly significant difference (p-value < 0.001) whereas many variables were not significantly different. HBA1c, FBG, and RBG were significantly higher in dyslipidemic subjects. Logistic regression analysis of risk factors and comorbidities in our patients revealed that age 60– 69 years and 70– 79 years had a significant association with comorbidities. Similarly, logistic regression analysis of risk factors and dyslipidemia in our patients revealed no statistically significant association.Conclusion: Our results observed that the comorbidities were associated with increasing age and common comorbidities were HTN, IHD, dyslipidemia. Our study has highlighted the current trends in T2DM symptomatology and comorbidities. Efficient management and control by early screening and developing healthy lifestyles in our patients can be very helpful in the prevention of all these highly morbid complications of this preventable disease.Keywords: dyslipidemia, DM, IHD, cholesterol, comorbidities, HbA1c, hypertension
format	article
author	Gazzaz ZJ Iftikhar R Jameel T Baig M Murad MA
author_facet	Gazzaz ZJ Iftikhar R Jameel T Baig M Murad MA
author_sort	Gazzaz ZJ
title	Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis
title_short	Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis
title_full	Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis
title_fullStr	Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis
title_full_unstemmed	Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis
title_sort	association of dyslipidemia and comorbidities with risk factors among diabetic patients: a retrospective analysis
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/01c66236b55d4cf38ea03975ff9e6792
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_version_	1718401106053169152

Association of Dyslipidemia and Comorbidities with Risk Factors Among Diabetic Patients: A Retrospective Analysis

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