Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses

Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses

ABSTRACT The live attenuated yellow fever virus (YFV) vaccine 17D stands as a “gold standard” for a successful vaccine. 17D was developed empirically by passaging the wild-type Asibi strain in mouse and chicken embryo tissues. Despite its immense success, the molecular determinants for virulence att...

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Autores principales: Maria Dolores Fernandez-Garcia, Laurent Meertens, Maxime Chazal, Mohamed Lamine Hafirassou, Ophélie Dejarnac, Alessia Zamborlini, Philippe Despres, Nathalie Sauvonnet, Fernando Arenzana-Seisdedos, Nolwenn Jouvenet, Ali Amara
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/01c8d676a9da462694b2b0beecc6ea31
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