Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity

Zhang et al. use mouse tumor models to show that the optimum treatment regime for Treg-induced radiation resistance is vaccine administration followed by radiation therapy. This finding could inform the design of future combinatorial cancer therapies in the clinic.

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Autores principales: Fayun Zhang, Zifeng Zheng, Apurba Kumar Barman, Zihao Wang, Luyao Wang, Wenfeng Zeng, Luoyang Wang, Yan Qin, Asmita Pandey, Chunling Zhang, Wei Liang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/01d4d619e60241cdae5b35a57c19f8bb
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spelling oai:doaj.org-article:01d4d619e60241cdae5b35a57c19f8bb2021-12-02T15:23:27ZOptimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity10.1038/s42003-020-01598-62399-3642https://doaj.org/article/01d4d619e60241cdae5b35a57c19f8bb2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01598-6https://doaj.org/toc/2399-3642Zhang et al. use mouse tumor models to show that the optimum treatment regime for Treg-induced radiation resistance is vaccine administration followed by radiation therapy. This finding could inform the design of future combinatorial cancer therapies in the clinic.Fayun ZhangZifeng ZhengApurba Kumar BarmanZihao WangLuyao WangWenfeng ZengLuoyang WangYan QinAsmita PandeyChunling ZhangWei LiangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Fayun Zhang
Zifeng Zheng
Apurba Kumar Barman
Zihao Wang
Luyao Wang
Wenfeng Zeng
Luoyang Wang
Yan Qin
Asmita Pandey
Chunling Zhang
Wei Liang
Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
description Zhang et al. use mouse tumor models to show that the optimum treatment regime for Treg-induced radiation resistance is vaccine administration followed by radiation therapy. This finding could inform the design of future combinatorial cancer therapies in the clinic.
format article
author Fayun Zhang
Zifeng Zheng
Apurba Kumar Barman
Zihao Wang
Luyao Wang
Wenfeng Zeng
Luoyang Wang
Yan Qin
Asmita Pandey
Chunling Zhang
Wei Liang
author_facet Fayun Zhang
Zifeng Zheng
Apurba Kumar Barman
Zihao Wang
Luyao Wang
Wenfeng Zeng
Luoyang Wang
Yan Qin
Asmita Pandey
Chunling Zhang
Wei Liang
author_sort Fayun Zhang
title Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
title_short Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
title_full Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
title_fullStr Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
title_full_unstemmed Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
title_sort optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/01d4d619e60241cdae5b35a57c19f8bb
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