Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients

Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients

Abstract Sepsis is a prevalent life-threatening condition related to a systemic infection, and with unresolved issues including refractory septic shock and organ failures. Endogenously released catecholamines are often inefficient to maintain blood pressure, and low reactivity to exogenous catechola...

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Main Authors: David Coquerel, Julie Lamoureux, Frédéric Chagnon, Kien Trân, Michael Sage, Etienne Fortin-Pellerin, Eugénie Delile, Xavier Sainsily, Justin Fournier, Audrey-Ann Dumont, Mannix Auger-Messier, Philippe Sarret, Eric Marsault, Jean-Paul Praud, Tamàs Fülöp, Olivier Lesur
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/01d655baf6da4408a83a36f90f682b23
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https://doaj.org/article/01d655baf6da4408a83a36f90f682b23

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