Repurposing of promoters and enhancers during mammalian evolution

Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Francesco N. Carelli, Angélica Liechti, Jean Halbert, Maria Warnefors, Henrik Kaessmann
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution.