Repurposing of promoters and enhancers during mammalian evolution

Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing...

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Main Authors: Francesco N. Carelli, Angélica Liechti, Jean Halbert, Maria Warnefors, Henrik Kaessmann
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a
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spelling oai:doaj.org-article:01df0f7d13964ee1b3ec70ae5ce9cc3a2021-12-02T15:34:28ZRepurposing of promoters and enhancers during mammalian evolution10.1038/s41467-018-06544-z2041-1723https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06544-zhttps://doaj.org/toc/2041-1723Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution.Francesco N. CarelliAngélica LiechtiJean HalbertMaria WarneforsHenrik KaessmannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Francesco N. Carelli
Angélica Liechti
Jean Halbert
Maria Warnefors
Henrik Kaessmann
Repurposing of promoters and enhancers during mammalian evolution
description Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution.
format article
author Francesco N. Carelli
Angélica Liechti
Jean Halbert
Maria Warnefors
Henrik Kaessmann
author_facet Francesco N. Carelli
Angélica Liechti
Jean Halbert
Maria Warnefors
Henrik Kaessmann
author_sort Francesco N. Carelli
title Repurposing of promoters and enhancers during mammalian evolution
title_short Repurposing of promoters and enhancers during mammalian evolution
title_full Repurposing of promoters and enhancers during mammalian evolution
title_fullStr Repurposing of promoters and enhancers during mammalian evolution
title_full_unstemmed Repurposing of promoters and enhancers during mammalian evolution
title_sort repurposing of promoters and enhancers during mammalian evolution
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a
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AT angelicaliechti repurposingofpromotersandenhancersduringmammalianevolution
AT jeanhalbert repurposingofpromotersandenhancersduringmammalianevolution
AT mariawarnefors repurposingofpromotersandenhancersduringmammalianevolution
AT henrikkaessmann repurposingofpromotersandenhancersduringmammalianevolution
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