Repurposing of promoters and enhancers during mammalian evolution
Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing...
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2018
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oai:doaj.org-article:01df0f7d13964ee1b3ec70ae5ce9cc3a2021-12-02T15:34:28ZRepurposing of promoters and enhancers during mammalian evolution10.1038/s41467-018-06544-z2041-1723https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06544-zhttps://doaj.org/toc/2041-1723Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution.Francesco N. CarelliAngélica LiechtiJean HalbertMaria WarneforsHenrik KaessmannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Francesco N. Carelli Angélica Liechti Jean Halbert Maria Warnefors Henrik Kaessmann Repurposing of promoters and enhancers during mammalian evolution |
description |
Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution. |
format |
article |
author |
Francesco N. Carelli Angélica Liechti Jean Halbert Maria Warnefors Henrik Kaessmann |
author_facet |
Francesco N. Carelli Angélica Liechti Jean Halbert Maria Warnefors Henrik Kaessmann |
author_sort |
Francesco N. Carelli |
title |
Repurposing of promoters and enhancers during mammalian evolution |
title_short |
Repurposing of promoters and enhancers during mammalian evolution |
title_full |
Repurposing of promoters and enhancers during mammalian evolution |
title_fullStr |
Repurposing of promoters and enhancers during mammalian evolution |
title_full_unstemmed |
Repurposing of promoters and enhancers during mammalian evolution |
title_sort |
repurposing of promoters and enhancers during mammalian evolution |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a |
work_keys_str_mv |
AT francesconcarelli repurposingofpromotersandenhancersduringmammalianevolution AT angelicaliechti repurposingofpromotersandenhancersduringmammalianevolution AT jeanhalbert repurposingofpromotersandenhancersduringmammalianevolution AT mariawarnefors repurposingofpromotersandenhancersduringmammalianevolution AT henrikkaessmann repurposingofpromotersandenhancersduringmammalianevolution |
_version_ |
1718386819478847488 |