Use of Soluble Extracellular Regions of MmpL (SERoM) as Vaccines for Tuberculosis
Abstract The current vaccine for tuberculosis (TB) is a live attenuated strain of Mycobacterium bovis (BCG) and while effective at reducing the potential for disseminated TB in young children its disease protection rates in adults is highly variable while it confers little protection against latent...
Guardado en:
Autores principales: | Emily J. Strong, Nicholas P. West |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/01e5b8b2db0b4b968747ff164106409d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Multiple Mutations in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> MmpL3 Increase Resistance to MmpL3 Inhibitors
por: Matthew B. McNeil, et al.
Publicado: (2020) -
Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria
por: Allison Fay, et al.
Publicado: (2019) -
Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport.
por: Chih-Chia Su, et al.
Publicado: (2021) -
The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation
por: Alice R. Moorey, et al.
Publicado: (2021) -
Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer
por: Akira Yokoi, et al.
Publicado: (2017)