Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus

Background: Hemoglobin A1c [HbA1c] is the best standard for measurements of glycemic control level in type 1 diabetes mellitus, especially in children. As iron deficiency anemia is a prevalent finding in children with diabetes, it may affect HbA1c levels in those children. Aim of the work: To det...

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Auteurs principaux:	Fatma El Nezely, Hussien Abd Elmaksoud, Magdy El Ghanam
Format:	article
Langue:	EN
Publié:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Sujets:	hemoglobin a1c (hba1c) iron deficiency anemia type-1 diabetes mellitus (t1dm) Medicine (General) R5-920
Accès en ligne:	https://doaj.org/article/01e81ad8e3a743b1a000f0423482376b
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spelling	oai:doaj.org-article:01e81ad8e3a743b1a000f0423482376b2021-12-02T14:10:53ZRelation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus2636-41742682-378010.21608/ijma.2020.46734.1193https://doaj.org/article/01e81ad8e3a743b1a000f0423482376b2021-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_124226_c9807179d980f7d48cc5afe149c5c914.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Hemoglobin A1c [HbA1c] is the best standard for measurements of glycemic control level in type 1 diabetes mellitus, especially in children. As iron deficiency anemia is a prevalent finding in children with diabetes, it may affect HbA1c levels in those children. Aim of the work: To determine the effects of iron deficiency anemia on hemoglobin A1c in type 1 diabetes mellitus Patients and methods:This was cross-sectional analytic study was done on 80 children with diabetes with type 1DM receiving insulin therapy; the patients divided into two groups, 21 diabetic children with iron deficiency anemia and 59 diabetic children with iron sufficient state, attending to the pediatric department of Al-Azher University Hospital in Damietta from February 2019 to September 2019. All children included were subjected to complete medical history, general examination, systemic examination, and laboratory investigations; [Complete blood count [CBC], HbA1c, Serum Iron, Serum Ferritin, Total Iron Binding Capacity, Fasting blood glucose, Post Prandial blood glucose, and ESR]. Results:In our study, we divided all patients [80 diabetic children] regarding glycemic control according to HbA1c value into three levels, the first level was optimal glycemic control level [HbA1c< 7.6%], the second level was suboptimal glycemic control [HbA1c 7.6 – 9.0%] and the third level was poor glycemic control level [HbA1c> 9.0%], there was a statically highly significant increase in HbA1c value of the iron-deficient diabetic group in compared to iron sufficient diabetic group at all levels of glycemic control. Conclusion: Iron deficiency anemia seems to increase HbA1c value in diabetic children Type 1, at the same degree of glycemia.Fatma El NezelyHussien Abd ElmaksoudMagdy El GhanamAl-Azhar University, Faculty of Medicine (Damietta)articlehemoglobin a1c (hba1c)iron deficiency anemiatype-1 diabetes mellitus (t1dm)Medicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 1, Pp 1075-1082 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hemoglobin a1c (hba1c) iron deficiency anemia type-1 diabetes mellitus (t1dm) Medicine (General) R5-920
spellingShingle	hemoglobin a1c (hba1c) iron deficiency anemia type-1 diabetes mellitus (t1dm) Medicine (General) R5-920 Fatma El Nezely Hussien Abd Elmaksoud Magdy El Ghanam Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus
description	Background: Hemoglobin A1c [HbA1c] is the best standard for measurements of glycemic control level in type 1 diabetes mellitus, especially in children. As iron deficiency anemia is a prevalent finding in children with diabetes, it may affect HbA1c levels in those children. Aim of the work: To determine the effects of iron deficiency anemia on hemoglobin A1c in type 1 diabetes mellitus Patients and methods:This was cross-sectional analytic study was done on 80 children with diabetes with type 1DM receiving insulin therapy; the patients divided into two groups, 21 diabetic children with iron deficiency anemia and 59 diabetic children with iron sufficient state, attending to the pediatric department of Al-Azher University Hospital in Damietta from February 2019 to September 2019. All children included were subjected to complete medical history, general examination, systemic examination, and laboratory investigations; [Complete blood count [CBC], HbA1c, Serum Iron, Serum Ferritin, Total Iron Binding Capacity, Fasting blood glucose, Post Prandial blood glucose, and ESR]. Results:In our study, we divided all patients [80 diabetic children] regarding glycemic control according to HbA1c value into three levels, the first level was optimal glycemic control level [HbA1c< 7.6%], the second level was suboptimal glycemic control [HbA1c 7.6 – 9.0%] and the third level was poor glycemic control level [HbA1c> 9.0%], there was a statically highly significant increase in HbA1c value of the iron-deficient diabetic group in compared to iron sufficient diabetic group at all levels of glycemic control. Conclusion: Iron deficiency anemia seems to increase HbA1c value in diabetic children Type 1, at the same degree of glycemia.
format	article
author	Fatma El Nezely Hussien Abd Elmaksoud Magdy El Ghanam
author_facet	Fatma El Nezely Hussien Abd Elmaksoud Magdy El Ghanam
author_sort	Fatma El Nezely
title	Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus
title_short	Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus
title_full	Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus
title_fullStr	Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus
title_full_unstemmed	Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus
title_sort	relation between iron status and hemoglobin a1c in children with type-1 diabetes mellitus
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/01e81ad8e3a743b1a000f0423482376b
work_keys_str_mv	AT fatmaelnezely relationbetweenironstatusandhemoglobina1cinchildrenwithtype1diabetesmellitus AT hussienabdelmaksoud relationbetweenironstatusandhemoglobina1cinchildrenwithtype1diabetesmellitus AT magdyelghanam relationbetweenironstatusandhemoglobina1cinchildrenwithtype1diabetesmellitus
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Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus

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