Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages

The origins of lineage correlations and heterogeneity in division and apoptosis times among single cells are incompletely understood. Here, a new lineage tracking data analysis approach reveals that circadian oscillations may underlie cell fate control and explain the observed correlation structures...

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Autores principales:	Shaon Chakrabarti, Andrew L. Paek, Jose Reyes, Kathleen A. Lasick, Galit Lahav, Franziska Michor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/01e9efd3bfb140d087a5b3c73a4ee514
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spelling	oai:doaj.org-article:01e9efd3bfb140d087a5b3c73a4ee5142021-12-02T15:34:29ZHidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages10.1038/s41467-018-07788-52041-1723https://doaj.org/article/01e9efd3bfb140d087a5b3c73a4ee5142018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07788-5https://doaj.org/toc/2041-1723The origins of lineage correlations and heterogeneity in division and apoptosis times among single cells are incompletely understood. Here, a new lineage tracking data analysis approach reveals that circadian oscillations may underlie cell fate control and explain the observed correlation structures.Shaon ChakrabartiAndrew L. PaekJose ReyesKathleen A. LasickGalit LahavFranziska MichorNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shaon Chakrabarti Andrew L. Paek Jose Reyes Kathleen A. Lasick Galit Lahav Franziska Michor Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
description	The origins of lineage correlations and heterogeneity in division and apoptosis times among single cells are incompletely understood. Here, a new lineage tracking data analysis approach reveals that circadian oscillations may underlie cell fate control and explain the observed correlation structures.
format	article
author	Shaon Chakrabarti Andrew L. Paek Jose Reyes Kathleen A. Lasick Galit Lahav Franziska Michor
author_facet	Shaon Chakrabarti Andrew L. Paek Jose Reyes Kathleen A. Lasick Galit Lahav Franziska Michor
author_sort	Shaon Chakrabarti
title	Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
title_short	Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
title_full	Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
title_fullStr	Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
title_full_unstemmed	Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
title_sort	hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/01e9efd3bfb140d087a5b3c73a4ee514
work_keys_str_mv	AT shaonchakrabarti hiddenheterogeneityandcircadiancontrolledcellfateinferredfromsinglecelllineages AT andrewlpaek hiddenheterogeneityandcircadiancontrolledcellfateinferredfromsinglecelllineages AT josereyes hiddenheterogeneityandcircadiancontrolledcellfateinferredfromsinglecelllineages AT kathleenalasick hiddenheterogeneityandcircadiancontrolledcellfateinferredfromsinglecelllineages AT galitlahav hiddenheterogeneityandcircadiancontrolledcellfateinferredfromsinglecelllineages AT franziskamichor hiddenheterogeneityandcircadiancontrolledcellfateinferredfromsinglecelllineages
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Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages

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