Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb
Pharmacologic interventions to halt/reverse the vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension (PAH) remains an unmet need. We previously demonstrated extracellular nicotinamide phosphoribosyltransferase (eNAMPT) as a DAMP (damage-associated molecular patter...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
SAGE Publishing
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/01ea69ffb6ab44d592257d77dde80f26 |
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