Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver
Abstract Sexual dimorphism in gene regulation, including DNA methylation, is the main driver of sexual dimorphism in phenotypes. However, the questions of how and when sex shapes DNA methylation remain unresolved. Recently, using mice with different combinations of genetic and phenotypic sex, we ide...
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Auteurs principaux: | Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S. Venkatesh, Qinwei Kim-wee Zhuang, Matthew L. Chang, Rachel A. Davey, Jeffrey D. Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K. Naumova |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/01f3318d5de14971bc8fe6b025ea3a3a |
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