Protein Biomarkers in Glaucoma: A Review
Glaucoma is a multifactorial disease. Early diagnosis of this disease can support treatment and reduce the effects of pathophysiological processes. A significant problem in the diagnosis of glaucoma is limited access to the tested material. Therefore, intensive research is underway to develop biomar...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/020766e79682408280871566406ed22c |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:020766e79682408280871566406ed22c |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:020766e79682408280871566406ed22c2021-11-25T18:02:21ZProtein Biomarkers in Glaucoma: A Review10.3390/jcm102253882077-0383https://doaj.org/article/020766e79682408280871566406ed22c2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5388https://doaj.org/toc/2077-0383Glaucoma is a multifactorial disease. Early diagnosis of this disease can support treatment and reduce the effects of pathophysiological processes. A significant problem in the diagnosis of glaucoma is limited access to the tested material. Therefore, intensive research is underway to develop biomarkers for fast, noninvasive, and reliable testing. Biomarkers indicated in the formation of glaucoma include chemical compounds from different chemical groups, such as proteins, sugars, and lipids. This review summarizes our knowledge about protein and/or their protein-like derived biomarkers used for glaucoma diagnosis since 2000. The described possibilities resulting from a biomarker search may contribute to identifying a group of compounds strongly correlated with glaucoma development. Such a find would be of great importance in the diagnosis and treatment of this disorder, as current screening techniques have low sensitivity and are unable to diagnose early primary open-angle glaucoma.Ewa FiedorowiczAnna CieślińskaPatrycja KukloAndrzej GrzybowskiMDPI AGarticleglaucomabiomarkerpeptideproteinglaucoma screeningeye-disorder screeningMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5388, p 5388 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
glaucoma biomarker peptide protein glaucoma screening eye-disorder screening Medicine R |
| spellingShingle |
glaucoma biomarker peptide protein glaucoma screening eye-disorder screening Medicine R Ewa Fiedorowicz Anna Cieślińska Patrycja Kuklo Andrzej Grzybowski Protein Biomarkers in Glaucoma: A Review |
| description |
Glaucoma is a multifactorial disease. Early diagnosis of this disease can support treatment and reduce the effects of pathophysiological processes. A significant problem in the diagnosis of glaucoma is limited access to the tested material. Therefore, intensive research is underway to develop biomarkers for fast, noninvasive, and reliable testing. Biomarkers indicated in the formation of glaucoma include chemical compounds from different chemical groups, such as proteins, sugars, and lipids. This review summarizes our knowledge about protein and/or their protein-like derived biomarkers used for glaucoma diagnosis since 2000. The described possibilities resulting from a biomarker search may contribute to identifying a group of compounds strongly correlated with glaucoma development. Such a find would be of great importance in the diagnosis and treatment of this disorder, as current screening techniques have low sensitivity and are unable to diagnose early primary open-angle glaucoma. |
| format |
article |
| author |
Ewa Fiedorowicz Anna Cieślińska Patrycja Kuklo Andrzej Grzybowski |
| author_facet |
Ewa Fiedorowicz Anna Cieślińska Patrycja Kuklo Andrzej Grzybowski |
| author_sort |
Ewa Fiedorowicz |
| title |
Protein Biomarkers in Glaucoma: A Review |
| title_short |
Protein Biomarkers in Glaucoma: A Review |
| title_full |
Protein Biomarkers in Glaucoma: A Review |
| title_fullStr |
Protein Biomarkers in Glaucoma: A Review |
| title_full_unstemmed |
Protein Biomarkers in Glaucoma: A Review |
| title_sort |
protein biomarkers in glaucoma: a review |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/020766e79682408280871566406ed22c |
| work_keys_str_mv |
AT ewafiedorowicz proteinbiomarkersinglaucomaareview AT annacieslinska proteinbiomarkersinglaucomaareview AT patrycjakuklo proteinbiomarkersinglaucomaareview AT andrzejgrzybowski proteinbiomarkersinglaucomaareview |
| _version_ |
1718411659722096640 |