Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

Oral ulcerations are sores of the mucous membrane of the mouth and highly prevalent in the population. Here, in a genome-wide association study, the authors identify 97 loci associated with mouth ulcers highlighting genes involved in T cell-mediated immunity and TH1 responses.

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Autores principales:	Tom Dudding, Simon Haworth, Penelope A. Lind, J. Fah Sathirapongsasuti, 23andMe Research Team, Joyce Y. Tung, Ruth Mitchell, Lucía Colodro-Conde, Sarah E. Medland, Scott Gordon, Benjamin Elsworth, Lavinia Paternoster, Paul W. Franks, Steven J. Thomas, Nicholas G. Martin, Nicholas J. Timpson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0209af871bee4da8988dc8ce22835fb5
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spelling	oai:doaj.org-article:0209af871bee4da8988dc8ce22835fb52021-12-02T17:33:11ZGenome wide analysis for mouth ulcers identifies associations at immune regulatory loci10.1038/s41467-019-08923-62041-1723https://doaj.org/article/0209af871bee4da8988dc8ce22835fb52019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08923-6https://doaj.org/toc/2041-1723Oral ulcerations are sores of the mucous membrane of the mouth and highly prevalent in the population. Here, in a genome-wide association study, the authors identify 97 loci associated with mouth ulcers highlighting genes involved in T cell-mediated immunity and TH1 responses.Tom DuddingSimon HaworthPenelope A. LindJ. Fah Sathirapongsasuti23andMe Research TeamJoyce Y. TungRuth MitchellLucía Colodro-CondeSarah E. MedlandScott GordonBenjamin ElsworthLavinia PaternosterPaul W. FranksSteven J. ThomasNicholas G. MartinNicholas J. TimpsonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tom Dudding Simon Haworth Penelope A. Lind J. Fah Sathirapongsasuti 23andMe Research Team Joyce Y. Tung Ruth Mitchell Lucía Colodro-Conde Sarah E. Medland Scott Gordon Benjamin Elsworth Lavinia Paternoster Paul W. Franks Steven J. Thomas Nicholas G. Martin Nicholas J. Timpson Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
description	Oral ulcerations are sores of the mucous membrane of the mouth and highly prevalent in the population. Here, in a genome-wide association study, the authors identify 97 loci associated with mouth ulcers highlighting genes involved in T cell-mediated immunity and TH1 responses.
format	article
author	Tom Dudding Simon Haworth Penelope A. Lind J. Fah Sathirapongsasuti 23andMe Research Team Joyce Y. Tung Ruth Mitchell Lucía Colodro-Conde Sarah E. Medland Scott Gordon Benjamin Elsworth Lavinia Paternoster Paul W. Franks Steven J. Thomas Nicholas G. Martin Nicholas J. Timpson
author_facet	Tom Dudding Simon Haworth Penelope A. Lind J. Fah Sathirapongsasuti 23andMe Research Team Joyce Y. Tung Ruth Mitchell Lucía Colodro-Conde Sarah E. Medland Scott Gordon Benjamin Elsworth Lavinia Paternoster Paul W. Franks Steven J. Thomas Nicholas G. Martin Nicholas J. Timpson
author_sort	Tom Dudding
title	Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
title_short	Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
title_full	Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
title_fullStr	Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
title_full_unstemmed	Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
title_sort	genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0209af871bee4da8988dc8ce22835fb5
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Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

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