Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis.
The selection and soaring spread of Mycobacterium tuberculosis multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) is a severe public health problem. Currently, there is an urgent need for new drugs for tuberculosis treatment, with novel mechanisms of action and, moreover, t...
Guardado en:
Autores principales: | Anna P Lucarelli, Silvia Buroni, Maria R Pasca, Menico Rizzi, Andrea Cavagnino, Giovanna Valentini, Giovanna Riccardi, Laurent R Chiarelli |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/020ddcb618bf440d8632e8218cc8863b |
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