Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis.

The selection and soaring spread of Mycobacterium tuberculosis multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) is a severe public health problem. Currently, there is an urgent need for new drugs for tuberculosis treatment, with novel mechanisms of action and, moreover, t...

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Autores principales: Anna P Lucarelli, Silvia Buroni, Maria R Pasca, Menico Rizzi, Andrea Cavagnino, Giovanna Valentini, Giovanna Riccardi, Laurent R Chiarelli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/020ddcb618bf440d8632e8218cc8863b
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